86 citations,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
75 citations,
March 2009 in “Journal of The American Academy of Dermatology” CCCA is a hair loss type affecting African women, possibly caused by grooming and chemicals, with various treatments and needing more research.
72 citations,
February 2011 in “American Journal of Biological Anthropology” The conclusion is that recognizing hair growth cycles can improve the precision of dietary and health assessments from hair analysis.
71 citations,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
71 citations,
February 2006 in “Clinics in Dermatology” Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.
69 citations,
January 2015 in “Current problems in dermatology” Trichoscopy is a quick, noninvasive method to diagnose hair and scalp disorders, often reducing the need for biopsies.
67 citations,
August 2007 in “American Journal of Pathology” Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
65 citations,
July 2006 in “Journal of biological chemistry/The Journal of biological chemistry” The gene Foxq1, controlled by Hoxc13, is crucial for hair follicle differentiation.
65 citations,
January 2005 in “American journal of clinical dermatology” Children with scalp fungal infections need proper diagnosis and treatment, usually with antifungal medications, and newer drugs may offer quicker recovery.
65 citations,
September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
65 citations,
June 2003 in “EMBO journal” Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.
63 citations,
January 1984 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth by increasing cell division and DNA synthesis.
60 citations,
March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
59 citations,
December 2016 in “Clinical, Cosmetic and Investigational Dermatology” Acne keloidalis nuchae is a tough-to-treat condition that greatly affects quality of life, especially in men of African descent.
55 citations,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
55 citations,
October 1992 in “Archives of Dermatology” Loose Anagen Hair Syndrome is a hereditary condition causing hair loss in children due to abnormal hair follicles.
54 citations,
January 1983 in “Archives of Dermatology” KFSD is a rare condition causing scarring hair loss, with no effective treatment known at the time of the report.
53 citations,
April 2021 in “Cell Host & Microbe” Skin bacteria, specifically Staphylococcus aureus, help in wound healing and hair growth by using IL-1β signaling. Using antibiotics on skin wounds can slow down this natural healing process.
53 citations,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
48 citations,
May 1991 in “The journal of investigative dermatology/Journal of investigative dermatology” Trichohyalin is also found in the outer layers of normal human skin.
47 citations,
December 2006 in “Therapy” The dietary supplement helped increase hair growth in women with hair loss.
47 citations,
June 1996 in “International Journal of Legal Medicine” Hair analysis for drugs needs a better understanding of how drugs enter hair, considering factors like hair structure and pigmentation.
47 citations,
November 2012 in “Pharmaceutical research” Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.
45 citations,
May 2003 in “Journal of Cell Science” α3β1-integrin is crucial for maintaining normal hair follicle shape and function but not needed for the development of the surrounding skin.
42 citations,
January 2011 in “Journal of Biomedical Optics” Infrared and Raman imaging can non-destructively analyze hair structure and help diagnose hair conditions.
41 citations,
June 2006 in “Journal of Investigative Dermatology” Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
40 citations,
July 2017 in “Frontiers in Medicine” Early and personalized treatment for hair loss in young people is crucial to prevent permanent damage and should include psychological support.
40 citations,
August 2018 in “Skin appendage disorders” Some alternative treatments for hair loss might work, but more research is needed.
39 citations,
January 2011 in “Archives of Dermatology” Reflectance confocal microscopy confirms that yellow dots are signs of damaged hair follicles in alopecia areata.
36 citations,
August 2018 in “Dermatologic Clinics” Trichoscopy is a useful tool for diagnosing hair disorders without pulling out hair.