14 citations
,
June 1982 in “Archives of Dermatology” This letter to the editor shares concerns about possible systemic effects from topical dinitrochlorobenzene therapy in a 25-year-old man treating alopecia areata.
20 citations
,
November 2014 in “JAMA dermatology” This study found that three treatments with the 810-nm diode laser improved skin texture and roughness/bumpiness in keratosis pilaris patients, although it did not reduce redness.
July 2024 in “Journal of Investigative Dermatology” A single medium, PRIME AIRLIFT, supports better human hair follicle formation in grafts.
15 citations
,
November 2016 in “Journal of The American Academy of Dermatology” This article discusses the potential of trichoscopy in diagnosing and treating dissecting cellulitis of the scalp and emphasizes the need for early diagnosis to prevent progression but reports no new clinical results.
7 citations
,
March 2018 in “Asian-Australasian journal of animal sciences” This study observed that the OCIAD2 and DCN genes in Liaoning cashmere goats have opposite effects on hair growth by interacting with the TGF-β signaling pathway, influencing follicle morphogenesis and periodic changes.
November 2022 in “Journal of Investigative Dermatology”
6 citations
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December 2021 in “Scientific Reports” This study found that inhibiting class I histone deacetylases in postnatal mouse dermal cells preserved their ability to induce hair follicles during culture by increasing specific gene expressions and activating the Wnt signaling pathway.
June 2020 in “Nihon Ika Daigaku Igakkai Zasshi” This study found that aPKCλ, but not aPKCζ, plays a critical role in maintaining hair follicle stem cell populations and promoting wound healing in the epidermis.
3 citations
,
December 2020 in “Skin Appendage Disorders” This case report highlights a family member with a confirmed diagnosis of hypotrichosis with juvenile macular dystrophy due to a CDH3 gene mutation, emphasizing the importance of genetic testing for accurate counseling.
28 citations
,
January 2005 in “Photochemistry and Photobiology” This study found that overexpression of PKCepsilon in mouse epidermis was associated with increased susceptibility to metastatic squamous cell carcinoma, potentially through a mechanism involving tumor necrosis factor-alpha.
82 citations
,
March 1992 in “Journal of Investigative Dermatology” 11 citations
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May 2013 in “Journal of Investigative Dermatology” KRTAP10 proteins help form the hair shaft's tough outer layer by interacting with specific hair keratins.
5 citations
,
January 2024 in “Science Advances” In this study, researchers identified Tenascin-C as a marker for touch dome keratinocytes, which maintain themselves and can develop into Merkel cells following injury, showing they share molecular traits with various epidermal keratinocytes.
March 2026 in “The Indian Journal of Animal Sciences” This study on Indian dromedary camel breeds investigated the KRTAP7 protein, finding all four breeds shared an identical gene sequence, with 13 phosphorylation and glycosylation sites influencing hair characteristics, alongside predicted interactions with other biosynthesis-related proteins.
25 citations
,
March 2019 in “Dermatologic therapy” This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.
November 2021 in “World Family Medicine Journal /Middle East Journal of Family Medicine” This study observed that diabetic ketoacidosis is common among type-1 diabetics, particularly with initial disease presentation or treatment discontinuation, and is more frequent in females and those with less educated or related parents.
38 citations
,
October 2001 in “British Journal of Dermatology” This study identified a new keratin, K6irs, as a potential histological marker for the inner root sheath of hair follicles in mice and humans, and as a candidate gene for hereditary hair defects.
January 2023 in “Journal of orthopedics & bone disorders” This study suggests that platelet-rich plasma's high levels of growth factors may be limited in promoting bone regeneration due to the concurrent release of Dickkopf-1, which inhibits osteogenesis.
January 2025 in “Journal of Bioresource Management” This study found that inhibiting the ATR kinase with VE-822 impairs DNA repair capability in quiescent human keratinocytes exposed to solar-simulated UV radiation, suggesting ATR's critical role in facilitating effective DNA damage repair and cellular recovery under UV stress conditions.
7 citations
,
April 1996 in “Archives of dermatological research” This study found that after topical application in rats, 1,24-dihydroxyvitamin D3 absorbed through both the stratum corneum and hair follicles, with about 30% excreted via the faeces.
1 citations
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September 2023 in “Life science alliance” In this study, researchers observed that Vdr-knockout mice experience hair cycle arrest during the catagen stage, leading to alopecia, with persistent epithelial strands forming in the hair follicles, indicating Vitamin D receptor's role in regulating hair follicle regression and regeneration.
22 citations
,
November 2016 in “International journal of molecular sciences” This study suggests that impaired VDR signaling in mice leads to dysregulated Ddit4 expression, impacting hair cycle progression and wound healing.
3 citations
,
January 2025 in “SAGE Open Medical Case Reports” In this case report, a 48-year-old woman with refractory discoid lupus erythematosus showed significant improvement, including hair regrowth, after treatment with deucravacitinib, suggesting its potential as an effective therapy for this condition.
26 citations
,
May 2007 in “Differentiation” This study suggests that Foxn1 acts as a brake on PKC signaling in keratinocytes, thereby modulating the stages of differentiation by controlling PKC activity.
35 citations
,
January 2008 in “American Journal of Clinical Dermatology” This case report further supports the association of keratosis follicularis spinulosa decalvans with acne keloidalis nuchae and tufted hair folliculitis.
11 citations
,
January 2021 in “British Journal of Dermatology” This report describes a new case of syndromic ichthyosis caused by compound heterozygous mutations in AP1B1, detailing the associated clinical features and molecular consequences in the patient.
November 2002 in “Hair transplant forum international” This article honors Damkerng Pathomvanich, MD, for his contributions to donor area harvesting, Asian hair, and advancing hair restoration in Thailand and reports no new research findings.
17 citations
,
November 2000 in “Journal of Investigative Dermatology” ZPK helps skin cells mature and may affect skin health.
June 2024 in “Lasers in Surgery and Medicine” This study found that the novel dermal cooling system was an effective and safe treatment for reducing pigmentation in benign pigmented lesions in Asian patients, with minimal side effects.
25 citations
,
July 2020 in “Journal of cosmetic dermatology” In this study, the authors reported that while deoxycholic acid effectively reduces submental fat, it can cause adverse effects such as edema, numbness, and skin necrosis, making knowledge of possible complications essential for clinicians.