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The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

Mutant mice help researchers understand hair growth and related genetic factors.

Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.

The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.

Keeping β-catenin levels high in mammary cells disrupts their development and branching.

A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.

DHT stops hair regrowth in mice, similar to human hair loss.

The Gas-Antisolvent process can be effectively modeled and optimized to create Finasteride, a hair growth drug.

Epidermolysis bullosa simplex causes easily blistered skin due to faulty skin cell proteins, leading to new treatment ideas.

K6hf is a unique protein found only in a specific layer of hair follicles.

Inhibiting ODC can prevent UV-induced skin cancer.

The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Different types of cells in the eye express specific keratins at various stages of development.

Nestin identifies specific progenitor cells in hair follicles that can become outer root sheath cells.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Increasing COX-2 in mouse skin causes bigger sebaceous glands and thinner hair, but stopping COX-2 can reverse hair thinning.

HSD11b1 affects skin nerves and increases non-histaminergic itch.

Scientists used stem cells to create a model of the skin disease Epidermolysis Bullosa simplex, which helped them understand its molecular mechanisms and could aid in finding treatments.

There are two types of stem cells in rodent hair follicles, each with different keratin proteins.