23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
321 citations,
January 2012 in “Cell stem cell” TGF-β2 helps activate hair follicle stem cells by counteracting BMP signals.
6 citations,
February 2021 in “Frontiers in Cell and Developmental Biology” Eating too much or too little vitamin A can cause hair loss.
1 citations,
January 2016 in “Asian-Australasian journal of animal sciences” The protein Gnαs is found more in black mice than white mice and may influence their coat color.
January 2020 in “Egyptian Journal of Dermatology and Venereology” People with alopecia have shorter hair follicles and more c-kit, a stem cell factor receptor, which could predict how the condition progresses.
30 citations,
August 2005 in “British journal of dermatology/British journal of dermatology, Supplement” A specific gene mutation causes hair loss and potential eye issues, even if vision seems normal.
9 citations,
June 2017 in “American journal of ophthalmology. Case reports” A new mutation in the CDH3 gene causes hair loss and vision problems in a young girl.
4 citations,
January 2018 in “International Journal of Trichology” A rare genetic disease causes sparse hair and early blindness due to a gene mutation.
3 citations,
January 2019 in “Annals of Dermatology” The study concluded that careful examination is key to differentiate between lipidized fibrous histiocytoma and juvenile xanthogranuloma.
1 citations,
October 2022 in “Rheumatology” RHUPUS should be considered in children with deforming arthritis.
1 citations,
June 2022 in “Chinese medical journal/Chinese Medical Journal” Two new mutations in the CDH3 gene cause hair loss and vision problems in a young girl.
1 citations,
April 2022 in “Rheumatology” Juvenile dermatomyositis can worsen quickly and needs strong treatment.
January 2022 in “Indian Journal of Paediatric Dermatology” A 13-year-old girl was diagnosed with juvenile lupus, showing only hair loss as a symptom.
August 2021 in “Indian dermatology online journal” A young boy with a rare skin and nail condition improved significantly with simple topical treatments.
March 2020 in “The Thai Journal of Veterinary Medicine” A Thai Bangkaew dog with diabetes and pancreatic issues improved with insulin, enzymes, and vitamins.
7 citations,
May 2012 in “Journal of veterinary diagnostic investigation” Some young Angus cattle had skin problems due to not enough vitamin A, which got better after they were given more vitamin A.
46 citations,
January 2015 in “Pediatric Rheumatology” Skin symptoms are important for diagnosing and managing juvenile-onset systemic lupus erythematosus and usually get better with treatment.
27 citations,
July 1997 in “PubMed” The harlequin ichthyosis mouse mutation causes thick skin and early death, resembling a human skin disorder.
19 citations,
May 2004 in “The American Journal of Dermatopathology” The research found that a specific gene mutation causes fewer hair follicles and disrupted hair growth cycles, leading to thin and short hair in people with Hypotrichosis with Juvenile Macular Dystrophy.
15 citations,
November 2012 in “Archives of Ophthalmology” A deletion in the CDH3 gene causes a rare disorder with short hair and vision loss.
8 citations,
January 2019 in “Acta dermato-venereologica” Some children with localized scleroderma are rarely resistant to methotrexate, and no common profile for resistance was found.
13 citations,
February 2012 in “International Journal of Dermatology” A new genetic mutation in the CDH3 gene causes hair loss and eye problems in young people.
4 citations,
March 2019 in “JAT. Journal of applied toxicology/Journal of applied toxicology” PFOS exposure disrupts hormone levels and enzyme activities in juvenile frogs, affecting males and females differently.
2 citations,
January 2012 in “PubMed” Mycophenolate mofetil is effective for treating severe lupus nephritis in children.
66 citations,
October 2002 in “Human molecular genetics online/Human molecular genetics” A gene mutation in mice causes skin defects and early death.
16 citations,
October 2014 in “Cell death and disease” FoxN1 overexpression in young mice harms immune cell and skin development.
26 citations,
November 1993 in “Progress in Neuro-psychopharmacology & Biological Psychiatry” Treatment during development affects hormone balance and sexual behavior in male rats.
24 citations,
July 2019 in “Cochrane library” Some treatments like methotrexate with prednisone might help juvenile morphea, but more research is needed to confirm.
Juvenile-onset lupus patients have more severe symptoms and need stronger treatment.
1 citations,
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Climate-related nutritional stress may cause hair loss in juvenile male Guadalupe fur seals.