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A mutation in the IKZF1 gene causes immune system overactivity, linked to autoimmune diseases like lupus.

Skin changes in women with PCOS are mainly due to hormonal imbalances.

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.

Digital gangrene can be an initial symptom of late-onset systemic lupus erythematosus.

Anifrolumab treatment improves quality of life and reduces disease activity and steroid use in SLE patients.

TB lymphadenitis can occur in people with SLE on long-term immunosuppressive therapy.

Many patients experience long-lasting symptoms like fatigue and pain after COVID-19, regardless of initial disease severity.

Significant progress was made in understanding PXE, but effective treatments are still needed.

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.

Most severe COVID-19 patients in Mexico experienced long-lasting symptoms that worsened their quality of life.

Long COVID causes a wide range of long-lasting symptoms that change over time and are hard to diagnose and treat.

A young woman with lupus developed tuberculosis due to weakened immunity from her medication, showing the need for better TB screening in such patients.

Light therapy may improve eye conditions by stimulating cell activity and increasing oxygen availability.

Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.

Colchicine might help treat different skin diseases, but more research is needed to confirm its effectiveness and safe dosage.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Antigen presenting cells around hair follicles are crucial in SLE-related hair loss.

ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Etanercept improved symptoms of a specific type of psoriatic arthritis in a patient who didn't respond to other treatments.

COVID-19 vaccines had more side effects and worse perception than flu vaccines in Korean lupus patients.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

A small forehead lesion led to the discovery of a significant brain arteriovenous malformation in a young girl.

Fungal infections can cause hair loss in lupus patients and should be considered even if rare.

Skin problems are common in lupus, often appearing first, with various types and treatments, and careful monitoring is important for diagnosis and management.

Chemotherapy can cause various skin reactions, with hair loss being the most common, and proper diagnosis and treatment of these reactions are important.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Aminopterin strongly suppresses epithelial tissues and can treat certain skin conditions but has significant side effects.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.