Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

This article reviews the use of hormonal therapies in dermatology, specifically focusing on their pathophysiologic rationale, indications, commonly used drugs, and pretreatment evaluations, and it reports no new research findings.

This study found that the LH response to nafarelin effectively distinguished gonadotropin deficiency from constitutional delay of puberty, performing comparably to the sleep test and offering certain advantages.

This study, using multimodal profiling in mice, found that various tissues contain unique γδ T cell subsets adapted to their environment, revealing their functional diversity, lineage relationships, and similarities to CD8+ tissue-resident memory T cells.

Non-viral vectors show promise for safe and effective CRISPR/Cas9 gene editing in treating diseases.

This study found that keratin coatings from human hair may improve the colony-forming efficiency of human mesenchymal stem cells by moderating donor variability, suggesting a potential use in clinical applications.

This study found that topically delivering KGF-1 DNA plasmid increased epithelial thickness and skin strength, suggesting potential benefits for strengthening compromised skin.

This study found that human outer root sheath cells express VEGF receptor-2, and exogenous VEGF165 significantly stimulates their proliferation through activation of the ERK signaling pathway.

This review discusses recent advances in the genetic understanding of inherited hair and nail disorders and reports no new clinical results.

This study found that hormonal antiandrogen acne treatment is associated with shorter antibiotic durations in women, suggesting early initiation may reduce overall antibiotic use.

This study found that thermoresponsive hydrogels can maintain mechanical memory in fibroblasts, enhancing wound healing compared to traditional trypsinized methods.

This study found that adding Wnt-10b to the culture medium of dermal papilla cells maintained their ability to induce hair follicles over 100 days in vitro.

This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.

This review examines the role of androgens in cutaneous disorders and the potential therapeutic effects of different oral contraceptives, noting variations in individual responses and the influence of genetic and local factors but reports no new clinical results.

This study found that the desolvation of finasteride hydrate solvates is highly dependent on the physical environment, complicating investigations but providing insight through complementary analysis techniques.

In this study, researchers identified a gene expression pre-pattern and implicated the Wnt inhibitor Dickkopf 4 in the formation of color patterns in domestic cat embryos.

This study found that repeated oral intake of 0.5 or 5 mg/kg of cobalt ferrite nanoparticles induced pulmonary toxicity in rats, with dose-dependent oxidative stress and inflammation observed, but no notable toxicity was seen at a 0.05 mg/kg dose.

This study found distinct gene expression patterns in the blood of alopecia areata patients, suggesting involvement of immune processes and new pathways like Wnt signaling and apoptosis in disease pathogenesis.

This review explores the diverse roles of rosemary, covering its nutritional and medicinal uses, cosmetic and pharmaceutical applications, and evaluates various extraction methods, with a focus on sustainable practices and commercial prospects.

This study established an androgen-responsive human organ culture model using hair follicles, demonstrating that women's intermediate facial follicles grow more hair in response to men's higher androgen levels.

This review discusses the migration and colonization of melanocytes from the neural crest in mammals and reports no new experimental results.

Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.

This study analyzed gene expression changes during the autumn coat color change in mountain hares and found conserved gene regulation with snowshoe hares, highlighting its role in seasonal camouflage adaptation.

This study suggests that synthetic steroid analogues or 5α-reductase modulation could be potential therapeutic strategies for nervous system disorders, but further research on their effects is necessary.

This report describes a study of estuarine bed-sediment quality in New Jersey and New York post-Hurricane Sandy, focusing on contamination extent and potential long-term impacts, with no new findings included.

This study reviews the mechanisms by which SARS-CoV-2 may impact male fertility, noting potential disruptions in spermatogenesis and hormone secretion, and underscores the need for follow-up in recovered men.

This review examines the recent progress in using bioactive molecules for skin regenerative medicine and reports no new clinical results; the authors suggest this method could become a promising strategy for in situ skin regeneration.

This study observed dynamic behaviors such as cluster formation, migration, and active proliferation of transplanted bone marrow cells in a mouse model, providing insight into cellular-level changes post-transplantation.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.