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Minoxidil effectively treats severe hypertension but has notable side effects.
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research Plasma Zinc Levels in Males with Androgenetic Alopecia as Possible Predictors of Conservative Therapy Effectiveness
Lower zinc levels may predict less effective hair loss treatment.
research Computational Derivation of a Molecular Framework for Hair Follicle Biology from Disease Genes
The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.
research Homologous Recombination Induced by Doxazosin Mesylate and Saw Palmetto in the Drosophila Wing-Spot Test
Doxazosin mesylate and saw palmetto cause genetic changes in fruit flies.
research The Rho GTPase Exchange Factor Vav2 Promotes Extensive Age-Dependent Rewiring of the Hair Follicle Stem Cell Transcriptome
Vav2 changes how hair follicle stem cells' genes work as they age, which might improve regeneration but also raise cancer risk.
research Genome Scan for Signatures of Adaptive Evolution in Wild African Goat (Capra Nubiana)
Wild African goats have genetic adaptations for surviving harsh desert conditions.
research Hair and Scalp
PRP may help with hair loss and improve hair quality with few side effects, but more research is needed.
research Scent of Telogen Effluvium
The document concludes that treating the underlying causes of telogen effluvium usually results in hair regrowth.
research Cell Polarization Defects in Early Heart Development
Defects in certain proteins cause major heart abnormalities during early development.
research Polycystic Ovary Syndrome (PCOS): An Inflammatory, Systemic, Lifestyle Endocrinopathy
PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.
research The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial
Platelet-rich plasma injections significantly improved hair regrowth and thickness in patients with hair loss.
research Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research Selection Signatures for Fiber Production in Commercial Species: A Review
Genomic research can help improve the quality and production of natural fibers in animals.
research Updates to Male Infertility: AUA/ASRM Guideline 2024
The 2024 guideline updates recommendations for genetic testing, imaging, and sperm retrieval in male infertility.
research Recent Updates of the CRISPR/Cas9 Genome Editing System: Novel Approaches to Regulate Its Spatiotemporal Control by Genetic and Physicochemical Strategies
CRISPR/Cas9 has improved precision and control but still faces clinical challenges.
research Secreted Subtilisin Sub3 from Microsporum Canis Is Required for Adherence to but Not for Invasion of the Epidermis
Sub3 is essential for fungus adherence but not for skin invasion.
research Scalp Immersion Proxigraphy: An Improved Imaging Technique for Phototrichogram Analysis
SIP is a better method for measuring hair growth accurately.
research Association Between Angiotensin-Converting Enzyme Gene Insertion Deletion Polymorphism and Androgenetic Alopecia Susceptibility Among Egyptian Patients: A Preliminary Case-Controlled Study
Certain gene variations may increase the risk of hair loss in Egyptians.
research Effect of Needle Geometry on Insertion Force of Different Hair Implanters
Needle shape affects the force needed for hair implants, with certain shapes reducing the effort required.
research Scd1 ab-Xyk: A New Asebic Allele Characterized by a CCC Trinucleotide Insertion in Exon 5 of the Stearoyl-CoA Desaturase 1 Gene in Mouse
A new mouse mutation causes skin and hair defects due to a gene change.
research Pattern of Tissue Invasion by Propionibacterium Acnes in Acne Vulgaris
The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.
research Novel Small-Insertion Mutation in the LIPH Gene in a Patient with Autosomal Recessive Woolly Hair/Hypotrichosis
Researchers found a new mutation in the LIPH gene of a woman with a rare hair condition.
research Mechanisms of Dermatophyte Invasion on New Zealand Rabbit Skin Models
The study found that injecting spores directly into rabbit skin effectively caused fungal skin infections, with symptoms worsening over time.
research Patentability of Dosage Regime Invention in the Form of Swiss-Type Claim Under Chinese Patent Law
Dosage regime inventions can be patentable in China, but legal uncertainty exists.
research IL-9 Mediated Human Primary Keratinocytes Invasion Is Dependent on MLC Controlled Contractility and Independent of MMP Activity
IL-9 increases skin cell movement but decreases their ability to invade, and this effect is controlled by cell contractility, not by MMPs.
research Genetic Fate-Mapping Reveals Surface Accumulation But Not Deep Organ Invasion of Pleural and Peritoneal Cavity Macrophages Following Injury
Cavity macrophages gather on organ surfaces but don't really invade or help repair the organs after injury.
research Atrichia With Papular Lesions Resulting From a Novel Insertion Mutation in the Human Hairless Gene
Researchers found a new mutation causing total hair loss from birth.
research Effect of Coconut Oil in the Management of Post-Denture Insertion Mucosal Changes: A Cross-Sectional Survey
Coconut oil effectively treats sore gums from new dentures and is safe, affordable, and heals quickly.
research Regulation of VDR by ΔNp63α Is Associated with Inhibition of Cell Invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin
The study presented a tracheal xenotransplantation assay as a simple in vivo system to evaluate epithelialization, hair follicle formation, and tumorigenesis using primary epidermal cells from wild-type and transgenic mice. This method involved seeding epithelial cells into deepithelialized rat tracheas, which were then transplanted into athymic nude mice. The study found that keratinocytes overexpressing ornithine decarboxylase (ODC) and infected with v-Ha-ras became invasive, penetrating all layers of the tracheal wall, similar to malignant skin carcinomas in ODC/Ras transgenic mice. The assay also demonstrated its utility in hair follicle reconstitution, showing that freshly harvested epithelial cells were more effective than cultured ones in forming hair follicles. The method proved advantageous for studying keratinocyte stem cell colonies and factors affecting hair follicle development, especially when cell numbers were limited.