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Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Targeting colon cancer stem cells might lead to better treatment results.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

New antifungal treatments for a children's scalp infection are effective and safe, but it's not decided if they will become the preferred option over the old treatment.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Air pollution (PM10) increases skin inflammation and aging by reducing collagen and may trigger a repair response in skin cells.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

Nanoparticles show promise for better wound healing, but more research is needed to ensure safety and effectiveness.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

PFS and PSSD are similar conditions with persistent sexual dysfunction after stopping medication.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Three new types of a skin blistering disease were found, caused by specific gene mutations.

CD98hc's role in skin health decreases with age.

The research concluded that selection significantly shaped the genetic variation of the X chromosome, with certain regions affected by past selective events.

Autophagy is crucial for normal sebaceous gland function and sebum composition.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Certain herbal compounds, especially from bitter melon, can inhibit cancer growth and promote hair growth by blocking PAK1.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Chemotherapy can cause brain inflammation and damage, and understanding this process could help manage side effects.