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Overexpression of HDGF in melanocytes does not cause cancer.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Covers common skin issues in kids, their diagnosis, treatment, and need for specialist care.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

Finasteride may cause gum problems, but stopping the drug can improve these issues.

Hair tourniquets on the clitoris are rare but can cause serious harm and should be removed quickly.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.

Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.

Removing a cat's pancreatic cancer can temporarily reverse hair loss caused by the disease.

Finasteride can cause gum swelling and bleeding, but stopping the drug helps recovery.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Food intake, not genetics, affects how the body processes tadalafil and finasteride.

First Korean case of Cronkhite-Canada syndrome with colon cancer and serrated adenoma.

A man with multiple autoimmune diseases developed liver injury from azathioprine, but his liver improved after stopping the drug.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Benign follicular mucinosis involves immune cells attacking hair follicles.

Overexpressing SSAT enzyme reduces prostate tumor growth in mice.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

Mitoxantrone is effective for treating acute leukemia, especially in older patients, with a lower risk of heart damage.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.

The Drug Ontology was updated to better classify drugs for hypertension, malaria, and opioid abuse, and to allow for more accurate research queries.