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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Too much androgen can cause hair loss; finasteride may help.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

Six new genetic regions linked to early hair loss also connect to Parkinson's disease and prostate cancer, possibly leading to new treatments.

The article concludes that better understanding gene regulation related to seasonal changes can offer insights into the mechanisms of seasonal timing in mammals.

The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.

Aromatase gene variation may increase female hair loss risk.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

The study identified and characterized new keratin genes linked to hair follicles and epithelial tissues.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Natural 5AR inhibitors effectively improve mild to moderate hair loss in men.

Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.