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9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Biotin deficiency in patients on total parenteral nutrition can cause serious symptoms but can be treated with biotin supplements.

Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.

Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.

Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.

New treatments are needed for PCOS that target its genetic, hormonal, and metabolic causes.

Anticancer drugs like methotrexate and trimetrexate could be effective and safe for treating malaria at low doses.

Vitamin D might help regulate insulin in the body, but taking Vitamin D supplements doesn't clearly prevent or improve type 2 diabetes. More research is needed.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

The review concluded that keeping the hair-growing ability of human dermal papilla cells is key for hair development and growth.

Androgens play a key role in causing PCOS (Polycystic Ovary Syndrome).

Notch signaling disruptions can cause various skin diseases.

New treatments for PCOS are improving fertility and managing symptoms better.

Sunscreens with higher SPF and UVA filters offer the best protection against skin aging from UVA rays.

Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.

The conclusion is that certain dog and cat breeds are prone to Malassezia dermatitis, which can be diagnosed with skin tests and treated with antifungal shampoos or medications, and preventing relapses involves managing underlying issues and maintaining good hygiene.

The guidelines help doctors manage skin problems from certain cancer treatments to improve patients' lives.

Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.

English springer spaniels are more prone to severe sebaceous adenitis than standard poodles.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Use antimalarials like hydroxychloroquine for cutaneous lupus, avoid herbal supplements, and focus on lifestyle changes like sun protection.

Blocking neurosteroid production can lead to more seizures and faster epilepsy onset in rats.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Hair cortisol is a reliable stress indicator in cattle but may not be valid for pigs.

Older men with low levels of a testosterone byproduct had a higher chance of developing an irregular heartbeat.

Family doctors can manage older men with urinary symptoms using exams, tests, and medications.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

New treatments like nanotechnology show promise in improving skin cancer therapy.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.