26 citations
,
November 2022 in “European journal of medical research” This review discusses the potential of nanoparticles to modify angiogenesis processes for therapeutic applications and reports no new clinical results, highlighting challenges and future prospects in treating angiogenesis-related diseases.
4 citations
,
April 2016 in “Journal of The American Academy of Dermatology” This case report details the first known instance of interferon-induced lichen planus in a seronegative HCV patient with metastatic renal cell carcinoma.
284 citations
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November 1999 in “Neurology” This article discusses the side effects of interferon beta therapy for MS, including flu-like symptoms and autoimmune reactions, and provides guidance on their management but does not report new clinical findings.
2 citations
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November 2004 in “Hospital pharmacy” This article reviews adverse drug reactions, emphasizes methods of prevention, and encourages reporting to the FDA's medWatch program, but presents no new study findings.
17 citations
,
January 1993 in “Journal of Gastroenterology and Hepatology” This study found that recombinant IFN α-2b injections in patients with acute post-transfusion hepatitis C can suppress viral RNA and lead to normalization of serum ALT, though long-term prevention of chronicity remains unclear.
November 2024 in “Journal of Investigative Dermatology” This study explored the effects of red ginseng-derived components on aging skin cells and found they do not have senolytic properties but can alleviate signs of cellular aging and improve skin cell function by reducing senescence markers and inflammation.
37 citations
,
October 2017 in “Clinical and Experimental Dermatology” This article discusses the potential of oral tofacitinib as a treatment for atopic dermatitis, alopecia areata, and vitiligo, without presenting new clinical results.
29 citations
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December 2022 in “Journal of Nanobiotechnology” In this study, IFN-γ-stimulated iPSC-derived mesenchymal stem cell extracellular vesicles improved atopic dermatitis in mice by reducing Th2 cytokine activity, suppressing inflammation, and restoring skin barrier function, as evidenced by decreased itching and inflammatory markers.
14 citations
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August 2018 in “Frontiers in Cellular and Infection Microbiology” This study found that dengue virus infection caused inflammation and cell death in human hair-follicle dermal papilla cells, which may contribute to increased hair shedding observed during the epidemic in Taiwan.
May 2025 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study found that immune privilege is preserved in hair follicles of nonsegmental vitiligo patients compared to those with alopecia areata, potentially protecting follicular melanocytes from autoimmune attacks.
April 2023 in “Journal of Investigative Dermatology” This study found that mRNA booster vaccinations for SARS-CoV-2 increased protective antibodies without worsening autoimmune disease activity in patients with pemphigus and bullous pemphigoid.
157 citations
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December 2015 in “Journal of the American Academy of Dermatology” This case study reported significant but temporary hair regrowth and skin repigmentation in a patient with vitiligo and alopecia areata during treatment with oral ruxolitinib.
74 citations
,
May 2016 in “Current opinion in pediatrics, with evaluated MEDLINE/Current opinion in pediatrics” This review identifies shared interferon gamma-driven immune pathways in vitiligo and alopecia areata, revealing potential targets for new treatments, but reports no clinical results.
27 citations
,
August 2010 in “Clinics in Dermatology” This article reviews the association between hepatitis C virus and systemic disorders like mixed cryoglobulinemia, highlighting potential autoimmune side effects from interferon-a2b treatments, and reports no new clinical results.
20 citations
,
December 2020 in “Frontiers in Immunology” This study found that certain T cell-associated genes were upregulated in dogs with Vogt-Koyanagi-Harada syndrome and vitiligo, suggesting a shared immunopathogenesis with humans.
19 citations
,
August 2017 in “American journal of clinical dermatology” This analysis reports that hepatitis B surface protein antigen exposure is associated with an increased risk of alopecia areata.
15 citations
,
March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that vitamin D receptor expression is associated with proliferating keratinocytes, while retinoid X receptor α is linked to differentiating keratinocytes, suggesting differential targeting by vitamin D metabolites.
11 citations
,
September 2024 in “Journal of the European Academy of Dermatology and Venereology” This review explores the shared pathogenesis of alopecia areata and vitiligo and compares treatment responses, noting that hair regrowth in alopecia areata occurs more rapidly than skin re-pigmentation in vitiligo, possibly due to differences in stem cell biology and treatment effects on melanocytes.
5 citations
,
June 2012 in “Journal of Investigative Dermatology” Harris et al. describe a new mouse model for vitiligo, where interfollicular melanocytes are retained and melanocyte-targeting immune responses are simulated, aiding the development of immunomodulatory therapies.
This chapter reviews recent developments in vitiligo research, highlighting the role of melanocyte stem cell differentiation and oxidative stress in its management, but reports no new clinical results.
2 citations
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March 2023 in “3C Empresa Investigación y pensamiento crítico” In this study, patients with alopecia areata showed significantly elevated serum levels of IFN-γ and severely deficient vitamin D3 levels compared to healthy controls.
1 citations
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October 2025 in “Journal of Allergy and Clinical Immunology” A JAK1 variant causes hair loss, skin issues, and thyroid disease, but treatment with a specific inhibitor can help.
1 citations
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April 2016 in “Journal of Investigative Dermatology” This study suggests that NKG2D+ Vδ1 T cells may contribute to hair follicle pathology in alopecia areata by recognizing stressed keratinocytes and inducing immune privilege collapse.
1 citations
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February 2022 in “Experimental Dermatology” This study found that the secretory profiles of adipose-derived stem cells vary between balding and non-balding scalp areas in androgenetic alopecia patients, suggesting involvement of angiogenic and inflammatory processes in the condition's development.
This study observed that, among alopecia areata patients in Fujian, China, lower IgG4 levels and higher IFN-γ levels were statistically significant, suggesting their potential role as biomarkers for the condition and highlighting avenues for future therapeutic developments.
October 2022 in “Faculty of 1000 Research Ltd” This review discusses the roles of various growth factors and cytokines in skin regeneration, highlighting their potential for future therapeutic development, and reports no new experimental findings.
This case study reports a rare co-occurrence of alopecia areata and vitiligo in a 13-year-old female, suggesting a potential pathogenic link between the two autoimmune skin diseases.
April 2016 in “Journal of Investigative Dermatology” This study suggests that lithocholic acid may enhance hair regeneration in alopecia by activating vitamin D receptors in human dermal papilla cells.
This study found that adipose derived stem cells in areas of alopecia in patients with androgenetic alopecia showed different levels of various signaling proteins compared to other scalp and periumbilical regions.
2 citations
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March 2021 in “Reproduction” This study found that finasteride may affect Ca 2+ signalling in human sperm by interacting with the PGE 1 -binding site, but its impact on fertilization requires further investigation.