18 citations
,
March 2009 in “Skin pharmacology and physiology” This study found that sunlight exposure causes significant structural and chemical damage to hair, including cuticle loss, cortex damage, and discoloration, with water playing a major role in discoloration of brown hair.
1 citations
,
July 2021 in “IntechOpen eBooks” This review discusses unspecific factors involved in the pathogenesis of skin diseases and potential ways cytokeratin changes might alleviate these conditions, but reports no new clinical results.
June 2017 in “Experimental dermatology” This article, a special issue on hair follicle biology and pathology, reports no new research findings.
May 2022 in “Голова и шея.” This report describes a case of a patient with metastatic renal cell carcinoma who developed a psoriasiform skin lesion while undergoing immune checkpoint inhibitor therapy.
January 2024 in “Journal of cutaneous and aesthetic surgery” In this clinical case report, a 10-year-old girl developed acute hair matting three weeks after scalp trauma and frequent povidone-iodine use, suggesting that scalp injuries and antiseptic overuse can be risk factors for this condition, especially when hair care is poor.
14 citations
,
January 2014 in “Cells Tissues Organs” This study found that single high-dose irradiation in mice induced more severe acute skin injury and hair depigmentation, while fractional doses led to longer-term damage in the dermis and subcutis.
1 citations
,
April 2025 in “Frontiers in Medicine” This editorial synthesizes research on UV-induced skin damage, highlighting potential therapeutic strategies by mapping cellular changes, identifying molecular mechanisms, demonstrating melanocyte protection, and proving combination therapy effectiveness in conditions like vitiligo.
November 2023 in “Journal of Investigative Dermatology” EGFR-targeted cancer therapy can cause skin issues starting at hair follicles, leading to inflammation.
4 citations
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November 2012 in “Dermatitis” A man got severe skin irritation after using marking nut sap for hair loss.
April 2023 in “Journal of Investigative Dermatology” In this study, trypsin digestion was found to be a faster and more efficient method than the explant technique for extracting bulge-derived keratinocytes from adult scalp biopsies.
14 citations
,
March 2014 in “Experimental and Molecular Pathology” This study found that sulfur mustard affects hair follicles and sebaceous glands in the skin by causing cellular damage, inflammation, and disrupting wound healing processes in hairless mice.
April 2018 in “Journal of Investigative Dermatology” This study found that combining CelluTome system and RCM is a safe and effective protocol for evaluating wound healing responses in patients with epidermolysis bullosa.
This chapter examines how toxins such as inorganic arsenic, dioxin, and bacterial toxins can disrupt the balance of keratinocyte stem cell regeneration and differentiation, affecting skin barrier maintenance.
August 2015 in “Free Radical Biology and Medicine” Some treatments can improve skin's defense against damage, but overuse may cause other skin problems.
37 citations
,
October 2021 in “Journal of Clinical Investigation” This study suggests that inflammation in the skin can exacerbate intestinal inflammation in inflammatory bowel diseases by activating fibroblasts in the colon through hyaluronan fragments released during skin inflammation.
19 citations
,
November 1985 in “Archives of Dermatology” This case study documented a black male newborn developing large bullae that healed with hypopigmentation, suspecting proteolytic enzymes in keratinocytes caused the collagenolysis responsible for the condition.
January 2019 in “Journal of the American Academy of Dermatology” This study found that many childhood cancer survivors at one institution delayed dermatologic care and had inadequate sun protection, risking late diagnosis of skin complications from cancer therapy.
This review discusses the complex process of wound healing and emerging areas of interest in wound treatment, reporting no new clinical findings.
May 2002 in “Journal of Investigative Dermatology” New findings on hair keratin, wound healing, and skin blistering were presented.
11 citations
,
July 2022 in “International Journal of Molecular Sciences” This study found that treating reconstructed human epidermis with beta-lipohydroxy salicylic acid increased tight junction remnants in the stratum corneum, potentially affecting skin cohesion and desquamation.
273 citations
,
May 2017 in “The Lancet” This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.
15 citations
,
October 2017 in “Clinics in Dermatology” This article reviews risk factors and warning signs of elder abuse in different settings, emphasizing the importance of dermatologists in correctly identifying potential abuse injuries, but presents no new clinical findings.
9 citations
,
July 2007 in “Journal of Investigative Dermatology” This study found that exposure to 12-O-tetradecanoyl-phorbol-13-acetate in mouse skin caused changes in claudin expression and localization, indicating disruption and eventual recovery of the epidermal barrier.
16 citations
,
April 2011 in “Journal of The American Academy of Dermatology” This article overviews dermatologic findings in forensic pathology and reports no new results; it emphasizes the importance of recognizing skin manifestations in identifying types of injury.
3 citations
,
October 2024 in “Cancers” In this study, 37.5% of patients with nodal or metastatic cutaneous melanoma treated with immune checkpoint inhibitors developed skin adverse events, primarily low-grade rashes, vitiligo, and other dermatological symptoms, occurring mainly after 10 weeks of treatment.
May 2026 in “International Journal of Cosmetic Science” This study found that UV radiation exposure during a simulated Brazilian summer caused more significant mechanical damage to natural hair than bleaching, although both caused comparable structural alterations, with double bleaching leading to the most severe protein degradation.
January 2015 in “Springer eBooks” Hair damage shows as fragility, dullness, and discoloration, varies by ethnicity, and is worsened by cosmetic procedures and diseases.
3 citations
,
January 1984
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that the loss of Langerhans cells in lichen planopilaris scars may be linked to the downregulation of ITG αvβ6, which is not seen in other scar formation diseases.
27 citations
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February 1991 This study found that extensive cuticle damage from diperisophthalic acid oxidation did not alter the tensile properties of human hair, suggesting that these properties are mainly due to the cortex rather than the cuticle.