11 citations
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January 2018 in “Acta dermato-venereologica” In this study, oral tofacitinib showed higher efficacy and tolerability in treating refractory alopecia totalis and universalis compared to traditional treatments, achieving a 50% improvement in severity scores for 44.4% of patients over six months, with fewer adverse effects.
In this pilot study, researchers found that ex vivo treatment with topical melatonin reduced chemotherapy-induced apoptosis and DNA damage in hair follicle stem cells of human scalp cultures, suggesting melatonin's potential as a protective agent against taxane-induced permanent hair loss.
December 2020 in “TURKDERM” This case report describes a 3-year-old boy diagnosed with temporal triangular alopecia, emphasizing the importance of clinical and dermoscopic examination for correct diagnosis due to the condition's rarity and risk of misdiagnosis.
18 citations
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May 1988 in “Journal of The American Academy of Dermatology” In this study, itraconazole was reported to effectively alleviate clinical symptoms in patients with recalcitrant Trichophyton rubrum infections, though toenail infections often recurred, indicating the need for further research on long-term efficacy and safety.
2 citations
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April 2017 in “Journal of Investigative Dermatology” In this study, tofacitinib treatment led to significant hair regrowth in 60% of patients with moderate-to-severe alopecia areata, suggesting potential for JAK inhibitors in treating this condition.
2 citations
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March 2023 in “Skin research and technology” This study observed that temporal triangular alopecia in infants presents with distinct clinical and dermatoscopic features, indicating the usefulness of dermatoscopy for diagnosis and differential diagnosis.
3 citations
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March 2021 in “Indian Journal of Rheumatology” This study presents a case where telemedicine allowed for early detection of a dermatomyositis flare during the COVID-19 pandemic using simple patient-reported measures, despite challenges in remote assessment.
This article lists the clinically important interactions and skin reactions of several drugs and substances, including THA, FK506, tamoxifen, tamsulosin, tartrazine, tea tree oil, temazepam, and temozolomide, but provides no new clinical results.
323 citations
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November 2017 in “Bioanalysis” This commentary discusses the challenges of matrix effects in LC–MS analysis and introduces the concept of a matrix effect factor using stable isotopically labeled internal standards to improve analysis reliability.
31 citations
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August 2001 in “PubMed” This study found that the TrichoScan method detected significant increases in hair counts and cumulative hair thickness in men after finasteride treatment, suggesting its potential for monitoring hair treatment responses.
6 citations
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December 2021 in “Journal of Cancer Research and Therapeutics” In this study, induction nab-paclitaxel plus cisplatin, combined with nimotuzumab and IMRT, followed by S-1 adjuvant chemotherapy, showed excellent survival benefits with tolerable toxicities for stage N3 nasopharyngeal carcinoma patients.
June 2024 in “BioSCIENCE” This study reviewed the use of microinfusion of microparticles (MMP®) with methotrexate for treating alopecia frontal fibrosante and found it reduced symptoms associated with the condition and improved specific scalp measurements, showing that the technique is safe and well-tolerated.
10 citations
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January 1994 in “Advances in pharmacology” This review examines the role of topoisomerase-interacting drugs in cancer treatment and emphasizes the importance of understanding their mechanisms for clinical development, but it presents no new results.
3 citations
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May 2023 in “International Journal of Molecular Sciences” In this study, researchers observed that phospholipid-calcium carbonate hybrid nanoparticles effectively delivered Tofacitinib citrate topically, which significantly inhibited hair follicle apoptosis and promoted hair growth in a mouse model of chemotherapy-induced alopecia, compared to a traditional Tofacitinib solution.
December 2025 in “eTheses of Maulana Malik Ibrahim State Islamic University (Maulana Malik Ibrahim State Islamic University)” This study found that the highest antioxidant-activity formulation of the RENTT herbal combination effectively stimulated hair growth in mice and may serve as a natural therapy for chemotherapy-induced alopecia.
July 2025 in “E-methodology” This study explored AI's potential in trichology services, finding it beneficial for diagnostics and treatment supervision, but noted the importance of addressing legal considerations, particularly in the Polish market.
12 citations
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June 2016 in “Clinical and Molecular Hepatology” This case report describes an autoimmune hepatitis patient who achieved remission with mycophenolate mofetil and corticosteroids after intolerance to azathioprine-based therapy.
November 2024 in “Communities in ADDI (University of the Basque Country)” Antisense oligonucleotides show promise for treating Myotonic Dystrophy type I.
August 2017 in “Seoul National University Open Repository (Seoul National University)” The study investigated the role of Aminoacyl-tRNA synthetase interacting multifunctional protein 1 (AIMP1) in hair follicle stem cell proliferation and its potential as a treatment for alopecia. AIMP1, when dissociated from the multi-tRNA synthetase complex, was found to be secreted by dermal papilla cells in a sonic hedgehog (Shh) signal-dependent manner. This secretion increased the proliferation of CD34+ hair follicle stem cells by promoting the wnt signaling pathway through inhibition of sFRP1, a known wnt antagonist. The research demonstrated that the N-terminal fragment of AIMP1 could be developed into a therapeutic peptide for hair loss. When applied topically to depilated mice, this peptide significantly accelerated hair growth, especially when formulated with carbomer. The findings highlighted a novel mechanism of AIMP1 action and its potential application in alopecia treatment.
This review discusses recent advances in noninvasive hair imaging technologies, such as global photography, trichoscopy, reflectance confocal microscopy, and optical coherence tomography, highlighting their potential to improve hair diagnostics and treatment monitoring, while also outlining their clinical applications and limitations.
3 citations
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July 2025 in “Clinical and Experimental Dermatology” This study reported that patients with alopecia areata treated with ritlecitinib in a real-life setting had a higher rate of positive response on the Severity of Alopecia Tool score compared to those in the ALLEGRO trial.
October 2025 in “Diagnostics” In this case study, an 18-year-old woman's triangular alopecic patch diagnosed as temporal triangular alopecia was considered non-progressive and had no impact on her quality of life, so no treatment was initiated.
April 2026 in “Human Genome Variation” In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.
3 citations
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April 2016 in “Journal of Investigative Dermatology” In this open-label trial, tofacitinib showed dramatic clinical responses in most patients with moderate-to-severe alopecia areata, supporting further research into JAK inhibitors for this condition.
6 citations
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November 2020 in “JAAD Case Reports” This study identified overlapping genetic susceptibility loci in both alopecia areata and inflammatory bowel disease, specifically with Crohn's disease and ulcerative colitis.
September 2023 in “International Journal of Applied Pharmaceutics” This study found that a topical gel containing Minoxidil and Tofacitinib citrate showed promise for treating alopecia areata, with formulation F5 demonstrating effective drug release and stability in evaluations.
20 citations
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January 2013 in “Annals of Dermatology” Topical minoxidil successfully treated temporal triangular alopecia.
1 citations
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November 2024 in “Frontiers in Immunology” This study provides an analysis of global publications on TLS, offering insights into the role of TLS in immunotherapy and suggesting future research directions.
3 citations
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August 2018 in “Medical Journal Armed Forces India/MJAFI” In this study, IPL treatment for six months significantly reduced hair growth in females with faun tail nevus linked to spinal abnormalities.
In this phase 2 trial, STS01 1% significantly improved hair regrowth in patients with mild to moderate patchy alopecia areata compared to placebo, with a manageable skin irritation side effect profile.