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In this case study, a 65-year-old male with hepatocellular carcinoma treated with the PD-1 inhibitor Sintilimab developed alopecia universalis alongside significant tumor regression and complete remission, highlighting a rare immune-related adverse event with effective anti-tumor outcomes.

Anti-PD-L1 immunotherapy can cause hair loss and unexpected hair color change, but treatment can restore hair growth and color.

This case study reports that adding adalimumab to a 12-year-old VKH patient's treatment allowed for ocular inflammation remission, vision improvement, and corticosteroid tapering, suggesting escalation of immunosuppression may be critical in pediatric VKH cases.

This case report highlights the rare occurrence of life-threatening aplastic anemia in a 65-year-old woman treated with temozolomide for glioblastoma multiforme, emphasizing the need for more frequent blood monitoring to detect severe bone marrow suppression early.

In a murine model of alopecia areata, this study observed that the IL-2 fusion protein HCW9302 helped prevent disease development by expanding regulatory T cells and reducing disease-causing effector T cell infiltrates, suggesting potential for using IL-2 fusion proteins in alopecia areata treatment.

This study found that pediatric HSCT recipients, especially those with chronic graft-versus-host disease, are at risk for developing various nonmalignant late cutaneous changes such as vitiligo, psoriasis, alopecia, and nail changes.

This case report describes the first successful use of telitacicept in treating a patient with systemic lupus erythematosus and a history of papillary thyroid carcinoma, suggesting its potential as a therapeutic option for such conditions.

This case report highlights the rarity and complex differential diagnosis of discoid lupus erythematosus, emphasizing that immunosuppressive therapy in such cases can lead to serious complications like pulmonary tuberculosis.

This article discusses the diagnosis and management of severe infections occurring alongside lupus flares in various patients but reports no new clinical results; the authors highlight the challenges and need for careful treatment strategies.

This review highlights the potential of microneedles for immunotherapy, emphasizing their ability to enhance immune responses and reduce side effects through precise and stimuli-responsive delivery, especially in tumor treatment, while also noting the limitations and areas for improvement in current systems.

This review examines therapeutic options for common pediatric skin conditions and reports promising results from immunotherapy, laser therapy, and bleach baths, but presents no new clinical findings.

This review discusses the human Nude/SCID phenotype and FOXN1 gene's role in immunological disorders affecting T-cell development but reports no new clinical findings.

This study found that folic acid deficiency in infant mice moderately worsened rotaviral disease, while zinc deficiency did not significantly affect rotaviral disease progression.

This study found that high skin expression of amphiregulin in acute graft-versus-host disease was associated with severe disease grade, poor overall survival, and increased non-relapse mortality.

This study found that IL18 signaling plays a crucial role in the homing and retention of mature regulatory T cells in the mouse thymus, primarily by upregulating the chemokine receptor CCR6.

In this study, pegylated interferon alfa-2b injections led to local cutaneous reactions, including cutaneous necrosis, in patients with hepatitis C and chronic myelocytic leukemia, requiring dose modifications or treatment withdrawal in some cases.

This case report describes an 87-year-old woman diagnosed with type 3 autoimmune polyendocrine syndrome, highlighting the importance of recognizing and managing coexisting autoimmune conditions.

This report documents a rare case of alopecia universalis in an HIV-positive patient in Portugal, highlighting the changing comorbidity spectrum in this population due to increased life expectancy from antiretroviral therapy.

In this study, researchers observed that dormant TRP-2+ melanoma cells in bone marrow can interact with CD8+ T cells in tumor-bearing ret transgenic mice, potentially influencing immune responses.

This narrative highlights a study underscoring that vitiligo and alopecia areata are complex autoimmune conditions, often misclassified as cosmetic, which can hinder patients' access to necessary treatments despite their profound impact on quality of life and associated comorbidities.

This report highlights the diagnostic challenge of distinguishing autoimmune hepatitis from visceral leishmaniasis in children, revealing the importance of excluding infectious causes closely mimicking autoimmune features before initiating immunosuppressive therapy.

This study found that targeting IL-6, IL-1, and CCR6 signaling pathways may effectively reduce irradiation-induced alopecia and dermatitis in radiotherapy patients.

This study demonstrates that an iPSC-derived skin organoid model effectively supports Merkel cell polyomavirus infection, persistence, and immune evasion, providing a valuable platform for studying viral tumorigenesis and testing treatment strategies.

This letter to the editor discusses immune checkpoint inhibitor-related alopecia and insights into its pathophysiology using non-invasive diagnostic techniques, but reports no new clinical results.

Tacrolimus treatment for autoimmune hepatitis can cause hair loss.

This study reported improvement in hair loss lesions in C3H/HeJ mice with alopecia areata following treatment with the CCR5 inhibitor maraviroc, alongside reduced infiltration of specific T cells in the lesions.

This report describes two cases where patients developed alopecia while undergoing treatment for psoriasis with IL-17 inhibitors, suggesting an unexpected paradoxical reaction.

This study reports that a novel gain-of-function mutation in TMEM173, combined with polymorphisms in TMEM173 and IFIH1, results in a distinct clinical phenotype with features of SAVI, including alopecia and photosensitivity.

In this case report, researchers described a severe case of myelosuppression and alopecia totalis in a patient with systemic lupus erythematosus following azathioprine treatment, highlighting the importance of monitoring for these uncommon side effects.

This review discusses the dynamic behavior of immune cells in skin immune responses using intravital imaging in mice and reports no new clinical results.