Immune Checkpoint Inhibitor-Related Alopecia: Insight into the Pathophysiology Using Non-Invasive Diagnostic Techniques

    January 2019 in “ Journal of dermatology
    Misaki Kinoshita‐Ise, F. Stuart Foster, Neil H. Shear
    Image of study
    TLDR Immune checkpoint inhibitors used in cancer therapy can cause hair loss, and understanding this can help manage the side effect.
    The letter to the editor discussed the pathophysiology of immune checkpoint inhibitor-related alopecia using non-invasive diagnostic techniques. The authors, Misaki Kinoshita-Ise and colleagues, provided insights into how these treatments, which are used in cancer therapy, can lead to hair loss. They emphasized the importance of understanding the underlying mechanisms to better manage and potentially mitigate this side effect. The study highlighted the use of advanced diagnostic tools to observe changes in hair follicles and scalp conditions without the need for invasive procedures.
    Discuss this study in the Community →

    Research cited in this study

    1 / 1 results

    Related Community Posts Join

    6 / 212 results

      community ~3 year update on my singular DHT immune hair for you guys

      in Update  21 upvotes 1 year ago
      The post is an update on the user's hair loss journey. They have a strong hair follicle that has remained unaffected by hair loss for almost 3 years. The user is starting finasteride and using ketoconazole, alfatradiol, and oral castor oil for hair maintenance.

      community The ultimate regiment to reverse hairloss

      in Treatment  6 upvotes 1 year ago
      The conclusion of the conversation is that the user "Shakalakaplaka" shares their comprehensive hair loss regimen, which includes various treatments targeting different pathways such as DHT, inflammation, fibrosis, immune system, testosterone, gut problems, and scalp health. The effectiveness of the regimen is not confirmed, and some users express skepticism or request before and after pictures for credibility.

      community Autoimmune issue?

      in Question  2 upvotes 6 years ago
      The user experienced severe hair loss, itchy scalp, and skin issues after trying no-shampoo, and wonders if it's male pattern baldness or an immune issue. They have a history of eczema, dermatitis, and jock itch, and have tried various treatments like coconut oil, peppermint, pumpkin seed, and onion.

      community Lost density 60% all over scalp in 120 days (4months)

      in Update  10 upvotes 5 months ago
      A user lost 60% hair density in 4 months, started finasteride and microneedling, and has greasy, flaky, yellowish scalp. They are awaiting biopsy results, and another user suggested trying ketoconazole shampoo.

    Similar Research

    5 / 1000+ results