19 citations
,
September 1999 in “Talanta” New method measures minoxidil concentration faster, more accurately, and automatically.
8 citations
,
March 2025 in “Journal of Drug Delivery Science and Technology” Dissolvable microneedles are a promising, painless method for effective skin treatments.
34 citations
,
July 2010 in “Expert Opinion on Drug Delivery” This review highlights the need for methodologies to understand and quantify drug penetration into hair follicles as significant drug pathways, noting this area lacks comprehensive articles and reports no new results.
11 citations
,
January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that LY320236 is a competitive inhibitor of type I and a non-competitive inhibitor of type II steroid 5alpha-reductase, indicating its potential as a dual inhibitor with differing modes of activity.
24 citations
,
December 2009 in “Future Medicinal Chemistry” This study identified new potential targets and indications for several marketed drugs using in silico profiling, suggesting opportunities for drug repositioning.
2 citations
,
June 2016 in “European Journal of Plastic Surgery” This study suggests recommendations for treating and referring patients with severe complications from dermal filler injections, highlighting the need for careful treatment to avoid scarring.
1 citations
,
January 1987 in “PubMed” This study reported that in a histopathologic analysis of five parenteral heroin users with candida folliculitis, candida and pseudohyphae were frequently found in association with hair follicles.
14 citations
,
March 2022 in “Macromolecular Rapid Communications” This review discusses the current state and potential future of polymer-based microneedles for transdermal drug delivery, without reporting new empirical results; it highlights their applications and existing challenges.
July 2024 in “Journal of Investigative Dermatology” PH-762 shows promise in treating skin cancer by effectively targeting and silencing PD-1 in tumors with minimal side effects.
March 2017 in “Iraqi Journal of Pharmaceutical Sciences” This study found that Iraqi male bodybuilders abusing anabolic androgenic steroids experienced significant changes in sex hormones, liver and kidney function, and lipid profiles compared to non-AAS-using controls.
5 citations
,
March 2016 in “Drug Development and Industrial Pharmacy” This article reviews the promising ease of drug administration via transdermal and other topical routes, highlighting their potential for high patient compliance and reduced side effects but provides no new clinical results.
21 citations
,
February 2021 in “BMJ case reports” This case study potentially links the use of anabolic steroids to increased severity of COVID-19 in a healthy 28-year-old man, with marked symptom improvement following treatment with proxalutamide.
April 2016 in “Journal of Investigative Dermatology” This study found that administering botulinum toxin A via Flex-PADs to mouse footpads inhibited sweating similarly to traditional injections, suggesting a promising patient-friendly delivery method for hyperhidrosis treatment.
6 citations
,
November 2004 in “Bioorganic & Medicinal Chemistry Letters” This study found that arylhydantoin and arylthiohydantoin derivatives with hydroxybutyl or methyl side-chains showed superior androgen receptor binding affinity and may serve as promising radioiodinated AR ligands.
7 citations
,
January 2025 in “Journal of Medicinal Chemistry” This study identified orally available itaconate derivatives that improve cellular permeability and bioavailability, with specific POC-based prodrugs showing significant inhibition of inflammatory cytokines in human epidermal keratinocytes and favorable oral pharmacokinetics, highlighting their potential for treating systemic and skin disorders.
5 citations
,
September 2014 in “Journal of Pharmaceutical Sciences” 9 citations
,
November 2022 in “International Journal of Molecular Sciences” This study found that LC-MS/MS assays provided more reliable and precise steroid measurements in human serum compared to traditional immunoassays, particularly at lower concentrations.
12 citations
,
April 2025 in “Discover Pharmaceutical Sciences” This review examines microneedle patches for drug delivery, detailing their designs, materials, manufacturing methods, and potential advantages, but reports no new clinical results.
May 2023 in “Current Medicinal Chemistry” This review highlights the potential of microneedle devices in dermatology for conditions like skin aging and autoimmune skin diseases, emphasizing their ability to facilitate targeted drug delivery by creating temporary skin pathways.
164 citations
,
January 2003 in “Drugs”
July 2011 in “مجله علمی پزوهشی دانشگاه علوم پزشکی ایلام” Testosterone reduces, while finasteride enhances, morphine's pain relief.
3 citations
,
June 2018 in “Bioorganic & medicinal chemistry” This study identified that derivatives 4, 4b, and 4c strongly inhibited the enzyme type 1 5α-reductase and decreased reproductive organ weights in hamsters, suggesting potential as prodrugs for prostate tumor growth inhibition.
19 citations
,
March 2019 in “International Journal of Dermatology” In this study, researchers measured that the MMP drug delivery technique administered approximately 1,175 μg/cm² of medication into the dermis of human skin, but these findings are specific to the experimental protocol used.
January 2015 in “Indo American Journal of Pharmaceutical Research” This article describes mesotherapy, a technique involving small doses of compounds injected into the skin for cosmetic uses like aging skin and fat reduction, and provides no new clinical results.
10 citations
,
August 2020 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” This minireview discusses the mechanisms of facial aging, examines current literature, and proposes filler injection protocols, but it reports no new clinical results.
6 citations
,
August 2016 in “Journal of women & aging” This study found that women with negative or mixed feelings about Botox and facial fillers reported diverse and sometimes persistent physical and psychological impacts, feeling commodified, fractured, abandoned, reflective, and transformed.
33 citations
,
November 2019 in “Journal of Controlled Release” In this study, researchers developed a new self-administered finasteride delivery system using powder-carrying microneedles that improved hair growth efficacy and addressed safety concerns compared to topical finasteride gel by allowing sustained intradermal release of the drug for three days with a single application.
January 2005 in “Fuzhou daxue xuebao. Ziran kexue ban” This study developed a rapid and efficient in vitro method using high-performance liquid chromatography to screen for steroid 5 alpha-reductase inhibitors, determining inhibition constants for Finasteride and Epristeride.
1 citations
,
July 2025 in “Journal of Clinical Medicine” In this review, experts discuss the low but significant risk of serious eye complications from popular minimally invasive cosmetic procedures like fillers and botulinum toxin injections, underscoring the need for awareness, careful patient selection, and adherence to safe practices to help prevent these outcomes.
This paper provides a comprehensive list of drugs including Ethamolin, Placidyl, Trecator-SC, Zarontin, Peganone, Didronel, and Lodine, detailing their indications, potential interactions, and reported adverse skin reactions, but it presents no new research findings.