21 citations
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January 2019 in “Lasers in Medical Science” This review found that low-level laser therapy significantly increased hair density in adults with androgenic alopecia compared to sham treatments, with greater effects observed at lower treatment frequencies.
September 2021 in “Medical lasers” Laser treatment followed by a special hair growth solution increased hair count and thickness without side effects.
9 citations
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August 2011 in “The World Journal of Men s Health” This study concluded that administering 5-alpha reductase inhibitors before photoselective vaporization of the prostate increased hemoglobin change, lasing time, and energy required during the procedure compared to controls.
147 citations
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January 2014 in “American Journal of Clinical Dermatology” This study found that low-level laser treatment with the HairMax Lasercomb significantly increased terminal hair density in both men and women with pattern hair loss, with no serious adverse events reported.
1057 citations
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November 2011 in “Annals of Biomedical Engineering” This review discusses the applications of low level laser therapy (LLLT) in wound healing, pain reduction, and treating various conditions, but reports no new clinical results; the authors highlight the need for randomized controlled trials for serious diseases.
February 2025 in “Lasers in Medical Science” This review discusses low-level laser therapy and fractional laser therapies as alternative treatments for androgenetic alopecia, but reports limited evidence of their efficacy due to small sample sizes and potential study biases.
March 1997 in “The American Journal of Cosmetic Surgery” A new hair transplant method showed promising results and a study found how deep a CO₂ laser can penetrate skin.
1 citations
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March 2018 in “Journal of lasers in medical sciences” This study found that combining topical capislow with laser hair removal significantly enhanced hair reduction compared to laser alone, although the beneficial effects lasted only while capislow was applied.
October 2021 in “Research Square (Research Square)” In this study, a 532 nm laser at 15 J/cm² increased the proliferation and tenogenic differentiation of tendon-derived stem cells in rats, mediated by Nr4a1 up-regulation.
2 citations
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February 2022 in “Biology” This study found that blue laser irradiation reduced ATP levels and cell viability in mouse skin by increasing oxidative stress through the production of reactive oxygen species.
165 citations
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August 2013 in “Lasers in Surgery and Medicine” This review discusses the potential mechanisms and evidence supporting low-level laser therapy for stimulating hair growth in men and women, while noting its safety and effectiveness but needing further study on specific parameters.
90 citations
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January 2009 in “Journal of cosmetic and laser therapy” In this study, low-level laser therapy showed no statistically significant improvements in hair growth measures, despite some patients experiencing increases in terminal hairs and shaft diameter.
1 citations
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January 2019 in “Journal of Nuclear Technologyin Applied Science (JNTAS) (Print)” This study found that low-level laser therapy accelerates skin regeneration in gamma-irradiated mice and enhances the biostimulatory effect on hair follicles.
This study found that low-level laser therapy significantly improved hair count and reduced hair loss in patients with alopecia areata of the scalp.
October 2025 in “Dermatologica Sinica” This study's network meta-analysis reported that botulinum injection combined with red laser and topical minoxidil is most effective for increasing hair density in androgenetic alopecia when using low-level laser therapy.
27 citations
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July 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This narrative review discusses the evolution and diverse medical applications of laser technologies, particularly in dermatology and skin biology, without reporting new research findings.
January 2019 in “The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology” This study suggests that low level laser therapy may be effective for alopecia compared to placebo, but current evidence is limited and studies show a high risk of bias.
January 2018 in “Clinical approaches and procedures in cosmetic dermatology” This review discusses clinical studies on low-level laser therapy for various types of hair loss and suggests it may be promising for those unresponsive to conventional treatments, but reports no new clinical results.
September 2024 in “Research Square (Research Square)” This study found that bi-weekly 1550nm low-level laser therapy significantly improved hair loss conditions and scalp health in participants, suggesting its potential as an effective non-invasive treatment option.
January 2021 in “Medpulse International Journal of General Medicine” This study found that low-level laser therapy significantly increased hair density and thickness in patients with androgenic alopecia over 8 and 16 weeks.
March 1996 in “The American Journal of Cosmetic Surgery” This article describes a surgical technique combining CO2 SilkTouch Laser and Calvitron Hair Transplant System that offers a natural-looking hairline with moderate session length and minimal bleeding, but reports no new clinical outcomes.
September 2012 in “Dermatologic Surgery” This review discusses the use of lasers and light sources for hair transplantation and pattern hair loss, noting past issues with CO2 lasers and suggesting further trials for low-level light laser therapy.
31 citations
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September 2014 in “Journal of Pharmaceutical Sciences” This study found that Er–YAG laser treatment significantly enhanced skin absorption and follicular delivery of antialopecia drugs, suggesting a potential laser-assisted approach to treat alopecia.
January 2000 in “Optics Letters” This study found that the maximum infrared temperature of laser-irradiated hair depends on melanin type, with eumelanin-rich hair reaching higher temperatures than pheomelanin-containing hair.
February 2010 in “Journal of The American Academy of Dermatology” This study found that NB-002 demonstrated clear antifungal activity and clinically significant nail clearing in subjects with distal subungual onychomycosis and ≤50% nail involvement, compared to a vehicle treatment.
19 citations
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August 2018 in “Journal of the American Academy of Dermatology” In this study, the researchers found that the picosecond pulsed alexandrite laser (PSAL) may be as effective and safe as the Q-switched alexandrite laser (QSAL) for treating freckles in Chinese patients.
32 citations
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September 2016 in “Dermatologic Surgery” This review discusses the current evidence and highlights gaps in research needed for the wider acceptance of low-level laser therapy as a treatment for hair loss; no new clinical results are provided.
January 2025 in “Medical Research Archives” This review discusses various applications of low level laser therapy and argues for a holistic evaluation of patients but reports no new clinical findings.
1 citations
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February 2022 in “Lasers in Medical Science” In this real-world study, low-level laser helmet therapy for androgenetic alopecia showed that male patients with specific scalp conditions may have better results after more than 180 uses or a year of treatment.
May 2023 in “Photobiomodulation, photomedicine, and laser surgery” In this study, 675 nm laser treatment significantly improved hair density and reduced miniaturization in both male and female patients with alopecia androgenetica, showing promising results without side effects after 10 sessions.