1 citations
,
January 2022 in “Open Journal of Endocrine and Metabolic Diseases” This case report describes a 70-year-old woman with pituitary resistance to thyroid hormone (PRTH) misdiagnosed as Graves disease, highlighting diagnostic challenges in managing this rare disorder.
January 2023 in “Radiation and Risk Bulletin of the National Radiation and Epidemiological Registry” In this study, heifers exposed to thyroid irradiation up to 30 Gy showed changes in thyroid hormone levels but tended toward recovery, without affecting immunity or productivity.
This study observed that intramuscular injection of sodium 131iodide at doses of up to 1 mCi can successfully induce hypothyroidism in rats without significantly damaging muscle or nearby tissues, despite concerns of adverse effects.
5 citations
,
September 2019 in “Journal of Biomedical Optics” This study determined in-vivo skin damage thresholds for 1319-nm laser exposure in pigs, and the findings may enhance understanding of thermal damage mechanisms and inform laser safety standards.
4 citations
,
April 2018 in “Journal of Investigative Dermatology” This study suggests that hydroxypinacolone retinoate (HPR) may be an effective alternative to tretinoin for anti-aging skin treatments, offering similar collagen production benefits without increased skin irritation.
3 citations
,
March 1992 in “Journal of clinical pathology” This review discusses the clinical evaluation and investigation needed for hirsute women, suggesting that most cases require minimal testing unless virilism or severe symptoms are present; no new clinical results are provided.
1 citations
,
April 2018 in “Journal of Investigative Dermatology” This study found that FZD2 is crucial for hair follicle formation and postnatal growth in mice and has a novel role in regulating early epidermal development, including stratification and cornification.
November 2024 in “Journal of Investigative Dermatology” Changes in scalp bacteria are linked to female hair loss, suggesting new treatment options.
July 2024 in “Journal of Investigative Dermatology” Alopecia areata causes negative emotions and stress due to hair loss and emotional triggers.
April 2018 in “Journal of Investigative Dermatology” This study found that ERBB2 mutations and amplifications are likely key drivers of extramammary Paget disease, suggesting potential for targeted therapies and cancer immunotherapy due to the moderately high mutational load observed.
April 2018 in “Journal of Investigative Dermatology” This study found that Mentha suaveolens aqueous extract activated Nrf-2 and increased detoxifying enzyme expression in keratinocytes, providing protection against oxidative stress without cytotoxicity.
April 2018 in “Journal of Investigative Dermatology” This study found that claudins CLDN1 and CLDN3 are crucial for maintaining proper hair follicle structure in mice, and their dysregulation may lead to telogen hair loss.
April 2018 in “Journal of Investigative Dermatology” This study reports that in aged mice, hair follicle dermal stem cells exhibit diminished self-renewal and preferential differentiation into dermal sheath cells, contributing to age-related hair loss.
April 2018 in “Journal of Investigative Dermatology” This study found that acne lesions and nonlesional skin in mild-to-moderate acne patients showed significant Th17-skewing and increased antimicrobials, suggesting systemic targets like IL-17/IL-23/IL-36 could be therapeutic.
April 2018 in “Journal of Investigative Dermatology” This study found that both Th1 and Th2 cytokine markers were elevated in the serum and skin of patients with alopecia areata, with Th2 markers more closely linked to disease severity.
April 2018 in “Journal of Investigative Dermatology” This study found that activation of the transcription factor Nrf2 in keratinocytes promotes wound healing in mice by expanding hair follicle stem cells, independent of changes in keratinocyte proliferation or migration.
April 2018 in “Journal of Investigative Dermatology” In this study, topical tofacitinib significantly promoted hair regrowth in mice, outpacing both minoxidil and controls over 21 days, with findings suggesting increased VEGF levels and decreased inflammation as possible mechanisms.
April 2018 in “Journal of Investigative Dermatology” The researchers reported that nicotinic acid normalized excessive sebaceous lipogenesis without affecting basal lipogenesis and suggested potential anti-acne benefits.
April 2026 in “Research Square” E13 fetal mouse fibroblast vesicles may help reduce scarring.
10 citations
,
October 2023 in “Mycoses” This study reviewed 131 cases of White Piedra and found it predominantly affects young women, often asymptomatic, with the presence of hair nodules commonly linked to hair-related factors such as long hair and use of hair accessories.
26 citations
,
January 1992 in “Carcinogenesis” This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.
2 citations
,
July 2007 in “Cancer biology & therapy” This study found that 86% of patients with follicular non-Hodgkin's lymphoma were alive and nearly two-thirds remained in complete remission eight years after initial treatment with the radioimmunotherapy drug Bexxar.
This source provides a comprehensive guide for general practitioners to enhance their skills in diagnosing and managing both common and clinically significant dermatological disorders, serving as a key reference in everyday medical practice.
21 citations
,
January 2013 in “Clinical Endoscopy” This study reports the first case in South Korea of Cronkhite-Canada syndrome associated with malignant colon polyp and serrated adenoma.
3 citations
,
June 2011 in “EFSA Journal” This review evaluates health claims regarding spermidine's contribution to normal hair growth and finds no evidence to support a cause-and-effect relationship.
9 citations
,
December 1958 in “Journal of Investigative Dermatology” 9α-21-difluoro-21-desoxyhydrocortisone is the most effective at stopping hair growth in rats.
4 citations
,
June 2013 in “The Journal of Rheumatology” This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.
1 citations
,
July 2012 in “EFSA Journal” The Panel concluded that there is no established cause and effect relationship between the specified vitamin and pumpkin seed oil combination and the maintenance of normal hair in healthy adults.
January 2016 in “Renal Failure” Kidney stones and hair loss are significantly related in people under 60 years old.
77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.