The Efficacy and Safety of Creating a Rat Hypothyroidism Model Through Intramuscular Injection of 131 Iodine

    September 2025
    Dafu Yu, Xinfeng Xie, Rui Zhou … Xiaoqing Zhou
    Studysummary This study observed that intramuscular injection of sodium 131iodide at doses of up to 1 mCi can successfully induce hypothyroidism in rats without significantly damaging muscle or nearby tissues, despite concerns of adverse effects.
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