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research A 20-year retrospective clinicopathologic study on melanoma in Singapore
This study found that bleach baths using 0.005% hypochlorite directly affected serine protease expression in skin cells and reduced skin pH in patients with atopic dermatitis, suggesting potential therapeutic benefits.
research Data Sheet 1_Effects of zinc supplementation on milk production performance and growth status of Bactrian camels.docx
This study found that zinc supplementation at 2.00 g/camel/day improved hair growth in lactating camels but did not affect milk yield or hump morphology, while 0.50–0.75 g/camel/day enhanced weight gain and hair development in calves.
research Examining the Utility of LA-ICP-MS for Detection of Time-resolved Zinc Exposures and Determination of Hair Growth Rate
This study found that while measuring zinc in hair did not allow calculation of individual hair growth rates, it effectively characterized zinc, lead, and mercury concentrations and improved methods for analyzing these exposures using LA-ICP-MS.
research Hague (Hag): A New Mouse Hair Mutation With an Unstable Semidominant Allele
This study mapped a spontaneous mouse hair mutation, "hague," to keratin genes on chromosome 15 but found no gene mutations in hague mice.
research Półilościowa ocena hirsutyzmu u 850 pacjentek z zespołem policystycznych jajników i 2988 kobiet z grupy kontrolnej w Chinach
This study found that hirsutism is more prevalent in Chinese women with PCOS compared to the general population, and the Ferriman-Gallwey score is a good predictor for diagnosing PCOS in this group.
research Androgenic alopecia associated with the HSD3B1 (1245a>c) in overweight women with polycystic ovarian syndrome
In this study, researchers observed that overweight Taiwanese women with PCOS who carry the HSD3B1 1245C allele have a significantly higher risk of developing androgenic alopecia compared to those with the wild-type allele.
research Skin regional specification and higher-order HoxC regulation
This study found that the unique crest feather formation in Polish chickens is driven by a 195-bp duplication in the HoxC10 gene region, which alters gene expression by modifying the genomic structure, suggesting a mechanism for diverse integumentary appendages in birds.
research 676 An underlying mechanism of hair loss in acrodermatitis enteropathica
Zinc deficiency causes reversible hair loss by disrupting hair growth and stem cell function.
research Author response: Lhx2 is a progenitor-intrinsic modulator of Sonic Hedgehog signaling during early retinal neurogenesis
This study found that the Lim-homeodomain transcription factor Lhx2 regulates Sonic Hedgehog signaling during early retinal neurogenesis in mice by controlling the expression of pathway genes in retinal progenitor cells.
research Alfuzosin/finasteride
research Alfuzosin/finasteride
research The MHS Hair Restoration Protocol: A Systems-Biology Integration of Nutritional Support, Microbiome Modulation, and Targeted Topical ECS Therapeutics
This research introduces the MHS Hair Restoration Protocol, which is a comprehensive approach aimed at restoring the hair follicle environment by modulating the gut-microbiome-endocannabinoidome axis and incorporating specific dietary and topical strategies, rather than focusing only on short-term hair count improvements.
research Glycogen Phosphorylase Inhibitor Promotes Hair Growth via Protecting from Oxidative-Stress and Regulating Glycogen Breakdown in Human Hair follicles
In this study, the researchers reported that a newly developed PYGL inhibitor, HTPI, enhanced hair growth in an ex-vivo culture by reducing oxidative damage in hDPCs and inhibiting glycogen degradation in hORSCs, showing potential as a treatment for hair loss comparable to minoxidil.
research Hair’s Zinc Level on Androgenic Alopecia
This study found that men with androgenic alopecia had significantly lower hair zinc levels compared to controls, but no significant difference in blood zinc levels was observed.
research Shortcutting the diagnostic odyssey: the multidisciplinary Program for Undiagnosed Rare Diseases in adults (UD-PrOZA)
This study reported that the Undiagnosed Disease Program at Ghent University Hospital successfully provided definite diagnoses for 18% of referred adults with suspected rare diseases, primarily through genomic technologies.
research Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling
This study found that deleting the Hes1 gene disrupts hair regeneration by delaying anagen initiation and shortening the anagen phase, suggesting it's crucial for maintaining hair cycle homeostasis.
research Zfp462 deficiency causes anxiety‐like behaviors with excessive self‐grooming in mice
In this study, a deficiency in the zinc finger protein Zfp462 in mice led to anxiety-like behaviors and excessive self-grooming, providing a new model for studying anxiety disorders.
research Facts About Zinc
This fact sheet discusses the impacts of zinc deficiency, including its effects on the immune system, cognitive function, and growth in children, and highlights the increased risk for those who consume alcohol excessively; it reports no new clinical results.
research Trace element zinc and skin disorders
This review discusses the use of zinc supplementation in dermatology for various skin conditions and reports no new clinical results, providing references for its application.
research Hairless Suppresses Vitamin D Receptor Transactivation in Human Keratinocytes
This study found that Hairless (Hr) acts as a corepressor of the vitamin D receptor (VDR) in human keratinocytes, blocking the action of vitamin D on keratinocyte differentiation.
research Overexpression of hypoxia-inducible factor-1α in hidradenitis suppurativa: the link between deviated immunity and metabolism
This study found that hidradenitis suppurativa is associated with increased serum levels of hypoxia-inducible factor-1α, suggesting its role in the disease's pathogenesis and as a treatment target.
research Rapid full engraftment and successful immune reconstitution after allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in Omenn syndrome
This report presents a case where a patient with Omenn syndrome, complicated by cytomegalovirus infection, was successfully treated using reduced intensity conditioning allogeneic HSCT from a sibling donor.
research Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency: Studies on the natural history of the defect and effect of androgens on gender role
This study in the Arab population of Gaza described pseudohermaphroditism due to 17β-HSD deficiency, where individuals showed marked masculinization after puberty despite inadequate androgen proportions.
research Molecular Basis for Hair Loss in Mice Carrying a Novel Nonsense Mutation (Hrrh-R) in the Hairless Gene (Hr)
This study found that a newly identified mutation in the hairless gene in mice led to decreased Hr mRNA levels and changes in gene expression related to hair follicle development.
research Hair follicle organoids: advances in construction, applications, and translational challenges
This review discusses hair follicle organoids as emerging models for studying hair biology and disorders, emphasizing their promise for bridging basic research and clinical applications, but reports no new results.
research Human Hairless Protein Roles in Skin/Hair and Emerging Connections to Brain and Other Cancers
This review discusses the role of the hairless protein (HR) in alopecia and cancer, noting its potential importance in cancer cell growth and survival, and reports no new experimental results.
research Zinc and copper levels in serum and hair in relation to somatic growth.
research Clinical response of alopecia, trichorrhexis nodosa, and dry, scaly skin to zinc supplementation
This study reported that oral zinc therapy improved hair and skin abnormalities in patients with dry brittle hair, alopecia, and other symptoms, regardless of demonstrated zinc deficiency.
research Possible relationship between poor skin disorders prognosis and serum zinc level: A narrative review
This review found a predominance of low serum zinc levels across various skin disorders, indicating possible value in further investigating zinc supplementation as an adjunctive therapy.