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This study demonstrated that the Epidermal Biopotential Sensing System (EBSS) can measure digital biomarkers of pain in mice, suggesting potential applications in assessing pain and screening analgesics in populations with communication difficulties.

This case report describes a rare instance of dermographic urticaria triggered by an 810 nm diode laser for hair removal, with symptoms managed effectively by pre-treatment with levocetirizine.

This study found that Dex-loaded hyaluronic acid hydrogel microneedles significantly reduced pain in an acute inflammatory visceral pain model without sedation, suggesting a promising and patient-friendly alternative to intravenous delivery.

This retrospective study found that applying local skin precooling before scalp nerve block significantly reduced injection site pain during PRP mesotherapy for patients with androgenetic alopecia, compared to those who did not receive precooling, thus improving patient comfort and compliance.

In this study, calcium imaging in transgenic mice revealed that non-neuronal TRPV4 in the skin enhances afferent signaling during electrical stimulation, suggesting a role for neuroimmune interaction in acupuncture signal initiation.

This study found that a topical henna formulation may improve symptoms like itching, burning, and redness in patients with recessive dystrophic epidermolysis bullosa, but larger controlled studies are needed.

This study suggests that the tumescent technique can improve hair micrografting by effectively providing anesthesia and reducing bleeding without the need for multiple needle injections or nerve blocks.

This abstract reviews the symptom of trichodynia, a painful scalp sensation linked to hair loss, and highlights its potential connection to inflammation but reports no new research findings.

In this study, researchers observed that P2X3-immunoreactive fibers extensively innervate the epidermis of rats, suggesting a primary role in detecting noxious stimuli in cutaneous tissue.

This review explores the roles of histamine receptors H2R, H3R, and H4R in treating various dermatoses but reports no new clinical outcomes.

This study observed that using ice pack compression or a vibration anesthesia device reduced pain during inactivated PRP scalp injections in patients with alopecia, suggesting both as inexpensive and accessible pain-relief options.

This article highlights the lack of research on the prevalence and characteristics of pain and itch in early stages of mild to moderate varicose vein disease, without reporting new findings.

This study found that subjective scalp sensations like hurting and burning are common among alopecia patients, with burning in particular showing a significant association with psychological distress in patients with lichen planopilaris and androgenetic alopecia, suggesting a potential psychoneuroinflammatory pathway.

This abstract provides no research findings or results; it outlines services and content types available through a health publishing platform.

This review examines current knowledge and treatment strategies for complex regional pain syndrome type I in adults, emphasizing clinical aspects and highlighting the lack of consensus on therapeutic approaches, without presenting new clinical findings.

This review discusses the characteristics, potential triggers, and challenges in diagnosing and treating sensitive scalp, reporting no new clinical results, and noting the need for further investigation.

This study reports that erythematous, infiltrated plaques can develop in patients receiving subcutaneous heparin therapy, indicating a possible delayed hypersensitivity reaction to heparin or its constituents.

This case report details a 5-year-old girl who developed allergic contact dermatitis and temporary excessive hair growth on her arm after a henna tattoo application.

The conclusion is that "trichoknesis" should be recognized as a separate condition from trichodynia, characterized by itching instead of pain.

Older adults may experience painful finger pitting due to nerve changes in aging skin, and treatments can help reduce symptoms.

This study identified that the MC-5-HT-HTR2A axis plays a role in chronic pruritus in a mouse model of SADBE-induced allergic contact dermatitis, suggesting potential for therapeutic targeting.

In this report, seven burn patients developed hypertrichosis after undergoing pressure garment/silicone therapy intended to prevent hypertrophic scarring.

The article discusses a complication that occurred during a follicular unit extraction hair restoration procedure, presenting an opportunity for the author to learn from the experience and reports no new research findings.

This study found that spinal strychnine enhances low threshold tactile responses in cat dorsal horn neurons, which may mirror pain states in humans that are less responsive to opioid treatments.

This study found that using a vibration anesthetic device during scalp mesotherapy significantly reduced pain in patients with androgenetic alopecia and alopecia areata compared to the non-vibration side.

Cold gel compresses are the best for pain relief during scalp microneedling.

This study observed an association between intense itching in anterior chest keloids and an increased density of nerve fibers in the epidermis, alongside elevated expression of the pruritus mediator substance P, though no difference was found in Langerhans cells related to pruritus, location, or region.

This study found that vibration assisted analgesia reduced pain during intralesional corticosteroid therapy for hair loss, enabling treatment in a broader range of patients, including those with needle phobia.

This study by Moore et al. (2025) provides the first evidence linking C-tactile afferents in humans to hair follicles, showing that these nerve fibers respond to hair movement rather than skin deformation, adding complexity to the understanding of their role in emotion and touch.

This study found that the Epilight multiple wavelength pulsed-intense light source was effective for long-lasting hair removal, particularly in individuals with dark hair and light skin.