13 citations
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April 2001 in “Journal of The American Academy of Dermatology” Using a vibrating device during injections can help reduce pain.
2 citations
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October 2017 Vibration anesthesia can significantly lessen the pain during hair restoration surgery.
April 2023 in “Journal of Investigative Dermatology” In this study, trypsin digestion was found to be a faster and more efficient method than the explant technique for extracting bulge-derived keratinocytes from adult scalp biopsies.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that mice lacking epidermal HSD11b1 had increased non-histaminergic itch and changes in skin nerve fibers, potentially linked to higher TSLP expression.
July 2026 in “Current Medical Issues” In this study, using EMLA cream did not adequately control pain during and after scalp PRP injections for androgenetic alopecia, with anxiety and younger age linked to higher pain levels.
11 citations
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August 2016 in “Journal of dermatological treatment” This study evaluated the effects of tip cryotherapy on idiopathic guttate hypomelanosis lesions, finding that 82.3% of treated lesions showed significant improvement after four months compared to only 2% of control lesions, with minimal side effects.
March 2005 in “Journal of The American Academy of Dermatology” Itch is a common symptom in patients with chronic venous insufficiency, often accompanied by burning and pain.
5 citations
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July 1999 in “Journal of Anatomy” This study found that methylene blue staining may reveal anatomical details of intraepidermal nerve fibre endings in the rat mystacial pad with greater clarity than the zinc iodide-osmium tetroxide technique.
2 citations
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January 2015 in “Case reports in neurological medicine” In this case report, pulsed radiofrequency neuromodulation provided over 80% pain relief for five months in a patient with chronic lesser occipital nerve pain after other treatments failed.
56 citations
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November 1993 in “Journal of The American Academy of Dermatology” Capsaicin cream quickly relieved itching in two patients with brachioradial pruritus.
5 citations
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November 2015 in “Journal of Cosmetic Dermatology” This review discusses pain management strategies for optical permanent hair removal, which causes pain due to the increase in skin surface temperature, but reports no new experimental results.
2 citations
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July 2016 in “Veterinary dermatology” This study reports that hyperaesthetic leucotrichia primarily affects Arabian and American paint horses, occurring mainly in summer, with histological differences from erythema multiforme despite some shared features.
8 citations
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September 2015 in “Journal of the European Academy of Dermatology and Venereology” This study observed that hair and scalp sensations were significantly more common and intense in chemotherapy patients compared to those receiving tamoxifen, with sensations ceasing after 11 weeks.
2 citations
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January 2022 in “Journal of the American Academy of Dermatology” This article discusses the use of virtual reality as a sensory distraction technique during intradermal injections for hair loss treatment and reports no new clinical results.
August 2020 in “Bioscience Biotechnology Research Communications” This study found that using topical anesthetic was more effective than a vibrating device in reducing discomfort from dental injections.
109 citations
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November 2011 in “Nature Neuroscience” November 2020 in “Journal of the American Academy of Dermatology” Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the occipital scalp had significantly higher epidermal nerve fiber density than the frontoparietal scalp, which may explain increased sensitivity in some patients.
October 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This study suggests that PGD2 may increase testosterone production in keratinocytes through oxidative stress pathways, with n-acetyl-cysteine blocking this effect.
1 citations
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September 2017 in “Dermatologic Surgery” The cephalic approach for nerve blocks is less painful than the anterior approach during hair restoration surgery.
October 2021 in “JAAD Case Reports” This article discusses diabetic gustatory hyperhidrosis as a rare form of autonomic dysfunction linked to severe diabetic neuropathy and nephropathy, noting its impact on social and emotional well-being.
1 citations
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September 2017 in “BMJ” The man has a disease causing skin patches, thickened nerves, and mild muscle weakness.
33 citations
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November 2012 in “JAMA Dermatology” In this study, 14 out of 15 women with scalp dysesthesia also had cervical spine disease, and gabapentin improved symptoms for some patients.
The man's scalp tightness after hair surgery affects his life and work, and it's unclear if it's due to the surgery or a mental health issue.
1 citations
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June 2015 in “Journal of anatomy” This study reported that novel kainate derivatives, especially ZCZ90, maintained potency in affecting proprioceptive sensory organ firing, aiding future receptor studies for potential treatment innovations.
April 2018 in “Selçuk Üniversitesi Tıp Fakültesi dergisi” This study found that repeated PRP injections in patients with androgenetic alopecia may lead to hyperalgesia, where pain is felt with less stimulus after each treatment.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that structural changes in the TRPV3 channel are linked to severe skin conditions like Olmsted syndrome, with differences observed between heat-activated and resting states.
This study presents a two-photon imaging method to visualize low-threshold mechanoreceptor axon terminals in live mouse forepaw skin, enabling repeated high-resolution imaging to study sensory circuits during development and adulthood.
1 citations
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January 2022 in “Dermatology Reports” This study reported that sensitive scalp symptoms, including trichodynia, are frequently found in hair loss patients, particularly among those with telogen effluvium and alopecia areata.
April 2023 in “Journal of Investigative Dermatology” This study demonstrated that the Epidermal Biopotential Sensing System (EBSS) can measure digital biomarkers of pain in mice, suggesting potential applications in assessing pain and screening analgesics in populations with communication difficulties.