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Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Cyclosporin A helps damaged hair follicles regrow hair quickly.

Hormonal therapy is a treatment option for acne, the only medical treatment for hirsutism, and the most promising for androgenetic alopecia.

Minoxidil effectively treats hair loss, works better for women, and requires consistent use.

Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.

Finasteride is a cost-effective option for treating BPH, reducing risk of urinary issues and surgery.

Minoxidil was first made for high blood pressure, but it was later found to help hair growth.

Minoxidil stops cells from making prostacyclin, which may help with hair growth. More research is needed.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

Taking tamsulosin or finasteride and being older increase the risk of floppy iris during cataract surgery.

Overweight smokers have worse hair loss.

Metabolic syndrome linked to female hair loss; waist size and high blood pressure important factors.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Women with polycystic ovarian syndrome are more likely to have cervical insufficiency, especially South Asian and Black women.

New compounds show promise for treating hair loss, enlarged prostate, and prostate cancer, with some being more effective and having different side effects than current treatments.

Most treatments for spondyloarthritis are safe, but monitoring and careful selection based on patient risks are important.

High levels of male hormones are very common in women with PCOS and affect their metabolism differently depending on their weight.

Adipose-derived stem cells show promise in treating skin conditions like vitiligo, alopecia, and nonhealing wounds.

Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.

Metabolic syndrome in kids and teens is linked to obesity and increases diabetes and heart disease risk; early lifestyle changes are crucial for management.

Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

Fat tissue treatments may help with wound healing and hair growth, but more research with larger groups is needed to be sure.

The article concludes that correctly diagnosing systemic causes of hair loss requires a detailed clinical evaluation and a systematic diagnostic approach.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Mild essential fatty acid deficiency can cause health issues and is worsened by low-fat diets.

Minoxidil overdose caused heart changes, treated with stomach wash, charcoal, and IV fluids.