10 citations
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October 2010 in “Hepatology” This case study suggests that treatment with Pil-Food, intended for hair loss prevention, may have triggered postinfantile giant cell hepatitis with autoimmune characteristics, which showed a rapid and effective response to corticosteroid therapy.
6 citations
,
June 2016 in “Journal of cellular biochemistry” This study found that the mammalian Hr protein can interact with the p53 pathway by binding to a specific p53 response element, influencing the regulation of genes involved in cell cycle control.
54 citations
,
January 2018 in “Scientific reports” This study used proteomics to identify various proteins in human hair, which may help develop novel biomarkers for hair health, disease, and aging.
2 citations
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January 2021 in “Cureus” This case report examines the long-term impact of extensive anabolic-androgenic steroid use on metabolic and cardiovascular health, highlighting adverse effects to guide primary care for this patient group.
25 citations
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November 2001 in “Kidney International” This study suggests that dihydrotestosterone plays a key role in the development of chronic allograft nephropathy, and inhibiting androgens may improve long-term kidney transplant outcomes.
In this case study, a 70-year-old male with lymphoid variant hypereosinophilic syndrome presented with rare isolated pulmonary involvement, which improved with prednisone treatment.
January 1996 in “Studia iuridica” This study identified two novel point mutations in the hHb6 gene associated with monilethrix, suggesting these mutations could serve as diagnostic markers for this genetic hair disorder.
32 citations
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October 2023 in “Biomedicines” This study found that chronic low-grade inflammation exists independently of excess weight or obesity in women with PCOS, with notable increases in specific cytokines such as IL-9, MCP-3, and MIP-1α.
1 citations
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July 2019 in “The journal of applied laboratory medicine” This review analyzes 873 cases of female hyperandrogenism, primarily attributing it to polycystic ovarian syndrome, and explores sample testing for suspected neoplasms but reports no new clinical findings.
August 1978 in “Dicp-The annals of pharmacotherapy” Crash diets can cause temporary hair loss, and professional medical advice can prevent serious health issues.
122 citations
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January 2006 in “Molecular & Cellular Proteomics” This study found that keratin and other hair proteins in humans are extensively modified posttranslationally, which helps explain the structural characteristics of mature hair.
80 citations
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October 1985 in “American Journal of Public Health” This study found significant weight loss and reductions in blood pressure and serum triglycerides among obese patients following a multidisciplinary program with a very low calorie ketogenic diet.
April 2023 in “Journal of Investigative Dermatology” This study found that human TMEM2 does not function as a hyaluronidase but is involved in regulating hyaluronan metabolism.
December 2024 in “Turkish Society of Clinical Biochemistry” This study found that women with idiopathic hyperandrogenemia had higher urinary Bisphenol A levels compared to healthy controls, suggesting a potential role of this chemical in the condition.
December 2025 in “Frontiers in Endocrinology” This study found that elevated CgA levels in PCOS are associated with obesity, insulin resistance, and low-grade inflammation, suggesting CgA may be a novel biomarker for metabolic risk stratification in PCOS.
December 2023 in “Benha Journal of Applied Sciences” This study found that male patients with androgenetic alopecia had higher serum levels of Zinc Alpha 2 Glycoprotein than healthy controls, suggesting its potential role in the disease's pathophysiology.
January 2018 in “Journal of Diabetic Association Medical College.” This case study reports a two and a half-month-old with biotinidase deficiency who showed rapid seizure improvement with biotin treatment after presenting with convulsions and neurological symptoms.
17 citations
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February 2003 in “Australasian Journal of Dermatology” This review discusses ovarian hyperthecosis as a rare cause of androgenetic alopecia in postmenopausal women and reports no new results; the authors highlight the need to explore its relationship to alopecia further.
January 2025 in “Haematology International Journal” This study describes a functional disorder in the ovary, known as stromal hyperplasia, characterized by the proliferation of ovarian stroma and luteinization of stromal cells, which is linked to excessive androgen production and elevated testosterone levels.
January 2020 in “Asian Journal of Basic Science & Research” This review discusses the role of Nutrease powder in managing hormonal disturbances in polycystic ovary syndrome and reports no new clinical results.
In this study, pruritus was the most frequent skin disorder observed in hemodialyzed patients, particularly among those undergoing long-term dialysis.
3 citations
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January 2011 in “International journal of trichology” Low DHEA-S levels might be linked to alopecia areata and could be a potential treatment target.
2 citations
,
May 2017 in “International journal of pharmacy and pharmaceutical sciences/International Journal of Pharmacy and Pharmaceutical Sciences” This review discusses genetic mutations associated with Hutchinson-Gilford progeria syndrome and reports no clinical results; the authors emphasize the importance of cardiovascular monitoring in management.
January 2026 in “Brazilian Journal of Development” This case study reported on a 62-year-old woman with ovarian hyperthecosis, which caused symptoms like hirsutism and elevated testosterone; after bilateral oophorectomy, her symptoms improved, suggesting the importance of considering this rare condition in hyperandrogenism diagnosis for postmenopausal women.
5 citations
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July 2024 in “Minerva Endocrinology” In this systematic review, an increase in hemoglobin and hematocrit was associated with testosterone therapy, especially within the first year, and factors like serum testosterone levels and therapy specifics were linked to erythrocytosis development, highlighting the need for further research to guide clinical practice.
October 2025 in “Journal of the Endocrine Society” In this case report, hyperandrogenism, including hirsutism and elevated testosterone, in a post-menopausal woman on anastrozole for breast cancer may be attributed to the drug after ruling out other serious causes like ovarian hyperthecosis.
This study suggests that raising the lower normal serum ferritin level to 50 ng/mL may improve organ functions even when hemoglobin levels are normal.
29 citations
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January 1996 in “The Journal of Clinical Endocrinology & Metabolism” This study identified a compound heterozygous mutation in the 3 beta-HSD gene that confirmed inherited 3 beta-HSD deficiency in a Pakistani child with salt-wasting congenital adrenal hyperplasia.
1 citations
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January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” This study developed a mouse model to mimic PHGDH gene copy number gain, finding that increased PHGDH expression leads to abnormal melanin production, which may offer insights into its role in melanoma.
1 citations
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February 2022 in “Case reports in endocrinology” This case report describes a 64-year-old postmenopausal woman with hirsutism due to a rare case of bilateral diffuse ovarian Leydig cell hyperplasia, leading to normalized testosterone levels and improved glycaemic control following surgery.