30 citations
,
June 2010 in “Endocrine Related Cancer” In this study, dutasteride more effectively reduced prostate cancer cell viability than finasteride in vitro, but did not significantly alter the angiogenic response.
8 citations
,
March 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that weakened anchorage of hair shafts, associated with the abnormal expression of 14-3-3σ, may contribute to alopecia in Er/+ mice.
January 2009 in “Bradford Scholars (University of Bradford)” The study observed that the tumor suppressor activity of bone morphogenetic proteins in mouse skin epithelium depends on Noggin levels, inhibiting Wnt and Shh signaling pathways to prevent tumor initiation and progression.
January 2003 in “Humana Press eBooks” This review discusses the roles of dihydrotestosterone in fetal development and adult diseases, reporting no new clinical results; the authors emphasize the potential of 5α-reductase inhibitors for treatment.
502 citations
,
February 2008 in “The Journal of Clinical Endocrinology & Metabolism” This review discusses hirsutism management guidelines, recommending androgen testing only for women with abnormal hirsutism scores and advocating for combined therapy approaches depending on severity and underlying conditions, but it reports no new clinical results.
59 citations
,
January 2021 in “Genes” This study reports identifying 12 candidate genes potentially involved in regulating hair follicle development in cashmere goats, which could contribute to improving cashmere production.
37 citations
,
January 2010 in “Journal of Clinical Investigation” In this study, N-WASP deficiency in mouse skin was found to cause severe alopecia and disrupt hair follicle cycling by 5 months, highlighting its critical role in skin function and Wnt signaling.
33 citations
,
October 2016 in “Photomedicine and laser surgery” This review discusses the development of IPL devices, highlights their established cosmetic uses, such as treating vascular and pigmented lesions, and suggests potential expansion into more effective combination therapies.
25 citations
,
November 2020 in “Proceedings of the National Academy of Sciences” This study found that the HoxC gene cluster plays a critical role in the development of ectodermal organs, including hair and nails, with mammalian-specific enhancers increasing transcription levels during development.
14 citations
,
August 2019 in “BioMed Research International” This study found that abdominal obesity was the primary predictive factor for nonalcoholic fatty liver disease in women, rather than the presence of polycystic ovary syndrome.
13 citations
,
September 2019 in “Clinical, Cosmetic and Investigational Dermatology” This review discusses the complex nature of erosive pustular dermatosis of the scalp, highlighting the challenges in diagnosis and management, and reports no new clinical findings.
11 citations
,
June 2017 in “Asian-Australasian journal of animal sciences” In this study, researchers found that the FoxN1, FoxE1, and FoxI3 genes are likely involved in hair follicle growth and development in cashmere goat fetuses.
3 citations
,
April 2019 in “Journal of the Endocrine Society” This case report describes a rare instance of Satoyoshi syndrome in a 27-year-old Asian American woman, notable for her normal ovarian function despite typical syndrome features.
1 citations
,
May 2022 in “International journal of molecular sciences” This study found that in Hutchinson–Gilford progeria syndrome, iPSCs committed to the keratinocyte lineage faster than normal cells, with LEF1 expression reduced and a partial rescue of the phenotype achieved through adenine base editing.
1 citations
,
January 2011 in “Brunel University Research Archive (BURA) (Brunel University London)” This study suggests that dutasteride does not present a significant risk to wild fish populations at typical environmental concentrations, but its notable bioaccumulation requires further investigation.
April 2026 in “BMC Genomics” This study identified key molecular differences between Long and Short hair type cashmere goats, suggesting hair type differentiation is linked to structural assembly and follicle remodeling.
April 2025 in “European Journal of Pharmaceutics and Biopharmaceutics” This study developed and tested Bicalutamide-loaded lipid vesicles in dissolving microarray patches for topical application, finding that they effectively deliver Bicalutamide through murine skin while maintaining a favorable safety profile, suggesting potential to improve treatments for androgenetic alopecia.
February 2024 in “Endocrinology and Disorders” This article compiles evidence on prescribing estrogen for hormonal imbalance in women, emphasizing it should be personalized and carefully managed by healthcare providers based on individual cases.
October 2023 in “Clinical case reports” This case study reports the first Palestinian case of an ovarian steroid cell tumor with virilization in a young female, highlighting the challenges in diagnosis and varied chemotherapeutic responses.
November 2020 in “Universal Journal of Pharmaceutical Research” In this study, tacrolimus-based treatment was found to result in fewer overall side effects compared to cyclosporine among Yemeni kidney transplant patients, although tacrolimus was associated with a higher incidence of diabetes.
2 citations
,
January 2014 in “Advanced Biomedical Research” This article describes SAHA syndrome, which includes symptoms of nodulocystic or severe acne, female pattern hair loss, and hirsutism, but reports no new results.
178 citations
,
April 2011 in “Journal of Clinical Investigation” This study found that the phenotype of Hedgehog/Gli-driven skin tumors in mice depends on the cell of origin, tissue context, and level of oncogenic signaling.
45 citations
,
August 2009 in “American Journal Of Pathology” Noggin promotes skin tumors by activating certain cell signaling pathways.
May 2025 in “Proceedings of the National Academy of Sciences” In this study, researchers found that the histone demethylase UTX is crucial for regulating skin differentiation through retinoic acid signaling, mainly impacting females, as males compensate with a Y-linked paralog.
January 2018 in “Journal of clinical and investigative dermatology” This study evaluated dermoscopic findings in patients with different types of primary cicatricial alopecias, suggesting trichoscopy may aid in differential diagnosis by revealing abnormalities in scalp structures.
102 citations
,
July 2020 in “International journal of molecular sciences” This review discusses the effects of hormonal changes on hair follicles, concluding that hormones like androgens and estradiol significantly influence hair growth and cycle, while the roles of other hormones are still being researched.
90 citations
,
April 2013 in “Dermatology online journal” This article reviews various medical treatments for hidradenitis suppurativa based on the author's experience with over 350 patients, but it reports no new clinical findings.
71 citations
,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the role of Edar signaling in hair follicle development and cycling, emphasizing its impact on cell fate, differentiation, and interactions with other pathways, but reports no new results.
38 citations
,
April 2017 in “PLOS Genetics” This study found that human progenitor keratinocytes form unique complements of enhancers and super-enhancers during differentiation and migration, influencing gene expression and skin disease variant enrichment.
20 citations
,
May 2011 in “Journal of Clinical Investigation” In this study, a transgenic mouse model was used to demonstrate that targeted cell loss in different tissues led to varying degrees of regenerative outcomes, including reversible impaired glucose tolerance, irreversible hair loss, and permanent moderate deafness.