Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study found that palmoplantar pustulosis patients exhibited oral dysbiosis, particularly among those with pustulotic arthro-osteosis, as compared to healthy controls.

This case report describes a 62-year-old woman who developed chin and upper lip hair growth after using bimatoprost for glaucoma, highlighting hirsutism as a possible side effect of prostaglandin analogues.

The study found that over-expressing ornithine decarboxylase in the outer root sheath of the hair follicle in mice increases UVB-induced tumor growth and invasive squamous cell carcinoma compared to inter-follicular epidermal keratinocytes.

This study found that epithelial keratin K 6 is associated with hyperkeratotic and ulcerated changes in the gastric pars oesophagea of pigs, suggesting epithelial proliferation plays a role in ulcer development.

This report introduces a new potential sign, paired ear creases of the helix, which may have relevance to cardiovascular disease similar to diagonal ear lobe creases, in a case of coronary artery disease.

This study found that androgens increase Odc1 expression in skeletal muscle myoblasts, promoting proliferation and delaying differentiation.

This study discovered that a specific G to C mutation in the ornithine aminotransferase gene is linked to the retarded hair growth phenotype in mice and may serve as a model for human gyrate atrophy.

This study found that modulating BMP activity in transgenic mice affects the development and characteristics of several ectodermal organs, such as skin, hair, and claws, highlighting a stage-dependent influence on organogenesis.

This case study in a 62-year-old postmenopausal woman highlights Leydig cell hyperplasia as a likely cause of hyperandrogenism of ovarian origin, where bilateral oophorectomy resolved the condition and confirmed the diagnosis through histopathological examination.

This study found that polycystic ovarian syndrome (PCOS) is the most common cause of cutaneous manifestations of hyperandrogenism in women of reproductive age, with hirsutism severity correlated to serum testosterone levels.

This study reported the case of a 30-year-old man with a bluish-grey scalp nodule that developed over a previously stable hairless plaque, revealing histopathological features consistent with epithelioid cell nests and spindle-shaped dermal melanocytes embedded in collagen.

This report describes the third known case of lipedematous scalp in a 51-year-old woman, marked by progressive thickening of the scalp without hair loss, and notes its association with early meningitis symptoms.

This article reviews the pathophysiology and causes of androgen-mediated hair growth in hirsutism but does not report any clinical outcomes; treatment aspects are discussed separately.

In this case report, a benign trichoadenoma was identified in a 42-year-old man as a skin-colored nodule on the cheek, with histopathology confirming the diagnosis and differentiating it from similar conditions like pilomatricoma and sebaceous cyst.

This study observed that transgenic mice with overexpression of HE4 developed keratitis and severe corneal opacity, suggesting that HE4 may significantly influence keratopathy and inflammatory responses in the eye.

This study presented a case series of erosive pustular dermatosis on the scalps of elderly patients, noting unusual presentation with hypergranulation tissue and unique dermoscopic vascular patterns, diverging from typical manifestations.

This article discusses challenges and limitations of using simple tissue mechanics for repairing head and neck skin defects in trauma and does not report new findings; it highlights potential problems with routine methods.

The GH-IGF-I axis is likely involved in the hormonal imbalances seen in non-obese women with functional hyperandrogenism.

In this case study, a postmenopausal woman with symptoms of virilization was diagnosed with a rare ovarian Leydig cell tumor, and surgical removal led to a resolution of her hyperandrogenism and related symptoms, highlighting the importance of thorough differential diagnosis in postmenopausal hyperandrogenism.

This article reviews the role of androgens in skin metabolism and diseases like acne and androgenic alopecia, but reports no new clinical results; the authors note unresolved issues regarding androgen interactions in skin structures.

This case report describes a postmenopausal woman with virilization linked to ovarian stromal hyperthecosis, highlighting the importance of detailed clinical evaluation and complementary testing for accurate diagnosis and treatment.

This source reports a rare case of a 10-year-old child developing periorbital milia as an unusual cutaneous manifestation of chronic graft-versus-host disease following allogeneic stem cell transplantation, suggesting that immune-mediated epidermal disruption may lead to milia formation.

This study suggests that BBS7 is crucial for maintaining PDL homeostasis by supporting Sonic hedgehog signaling activity, with occlusal hypofunction leading to its downregulation and associated tissue changes.

In this case report, the authors describe the diagnosis and management of a rare case of hyperandrogenism in a postmenopausal woman, attributed to coexisting ovarian Leydig cell and Brenner tumors, with improvement in symptoms following bilateral salpingo-oophorectomy.

This case study reports that a heterozygous missense GJA1 mutation, p.Gly138Ser, in a 2-year-old boy with oculodentodigital syndrome primarily resulted in syndactyly, fifth finger hypoplasia, and hypotrichosis, without neurological or craniofacial abnormalities.

In this study, researchers used advanced RNA sequencing techniques to discover that communication between specific fibroblast and myeloid cell populations may play a role in acne keloidalis, and found that corticosteroid injections could significantly reduce disease activity and gene expression related to these cells.

This review identifies excessive sebum, decreased elasticity, and increased hair follicle volume as key factors contributing to enlarged skin pores, emphasizing the need for individualized treatment based on underlying causes.

This study conducted physical examinations on fifty women with hirsutism, focusing on virilization signs, but reports no new clinical findings.

This report describes two cases of aplasia cutis congenita with hair collar signs and hemangioma, which may suggest neural tube defects, although imaging showed no bone or neural tissue abnormalities.

This letter to the editor raises the possibility of a new medical entity characterized by symptoms such as poikiloderma, hyperpigmentation, alopecia, malformed bones, lymphedema, and decreased cortisol, but provides no clinical results.