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Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Cancer development is like natural selection, involving mutated cells and environmental factors.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

SHBG may be a useful early indicator and treatment target for PCOS.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

High levels of androgens during early development may cause PCOS-like symptoms.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Melatonin may help treat PCOS symptoms in rats.

Eating high glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.

Female hair loss linked to metabolic syndrome, not in males.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Menstrual disorders are common in adolescents and can be influenced by weight, activity, and health issues, requiring careful evaluation and more research for effective treatment.

Women with polycystic ovary syndrome tend to have a longer anogenital distance.

Insulin-sensitizing drugs like metformin can help with ovulation, weight loss, and lower testosterone in some women with PCOS.

Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Severe baldness on the top of the head is linked to a higher chance of heart disease, especially in men under 60.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Greek women with PCOS have a higher risk of metabolic syndrome and are more likely to be overweight compared to healthy controls.

The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.

The document concludes that there are still unknowns about the effectiveness, risks, and detection of performance-enhancing drugs, and doping remains a challenge.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.