23 citations
,
March 2009 in “Skin Pharmacology and Physiology” This study found significant hormonal differences, including elevated cortisol and androstenedione levels, in both male and female androgenic hair loss patients compared to controls, suggesting complex hormonal interactions in the condition.
118 citations
,
February 2009 in “Fertility and Sterility” This study found that approximately 75% of women with PCOS exhibited hyperandrogenemia, with free testosterone being the most frequently elevated marker.
4 citations
,
December 2018 in “Case reports in endocrinology” This case study reported a postmenopausal woman with a testosterone-secreting ovarian tumor that was not detected through standard clinical or radiological examination but was found via biopsy.
January 1986 in “Journal of Steroid Biochemistry” Women with severe acne, hirsutism, and androgenic alopecia often have higher levels of certain androgens, but the specific pattern can't be predicted just by looking at symptoms.
10 citations
,
April 2018 in “Maturitas” This review discusses hormonal changes during menopause, emphasizing the relative androgen excess and the role of insulin resistance, and reports no new clinical findings.
15 citations
,
September 1973 in “PubMed” This study observed that in cases of moderately severe male-pattern hirsutism, elevated free plasma androgen levels occur in 85% of patients, suggesting a subtle hyperandrogenic state as a common underlying factor.
12 citations
,
January 2009 in “Gynecological Endocrinology” This case report identified ovarian hyperthecosis as the cause of recent-onset androgenic symptoms in a 73-year-old woman, which was confirmed by ovary removal and led to symptom improvement.
11 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” This case study describes an extremely rare instance of androgen-secreting adrenocortical carcinoma in a patient with non-classical congenital adrenal hyperplasia.
1 citations
,
January 2021 in “Prague medical report” This article reviews the potential male equivalent of polycystic ovarian syndrome, focusing on hormonal alterations and premature androgenic alopecia, but reports no new clinical findings; the authors highlight the need for further studies on adrenal steroids and other factors.
1 citations
,
June 2021 in “Revista de la Facultad de Ciencias Médicas de Córdoba” This case report describes a postmenopausal woman with virilization linked to ovarian stromal hyperthecosis, highlighting the importance of detailed clinical evaluation and complementary testing for accurate diagnosis and treatment.
54 citations
,
February 1993 in “Endocrine reviews” This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.
November 2023 in “JCEM Case Reports” In this case report, a 55-year-old postmenopausal woman was diagnosed with ovarian hyperthecosis as the cause of her hyperandrogenism after detailed hormonal and imaging investigations, which was successfully treated with bilateral salpingo-oophorectomy, leading to symptom improvement and normalized testosterone levels.
December 2024 in “Turkish Society of Clinical Biochemistry” This study found that women with idiopathic hyperandrogenemia had higher urinary Bisphenol A levels compared to healthy controls, suggesting a potential role of this chemical in the condition.
26 citations
,
April 2007 in “Journal of pediatric gastroenterology and nutrition” This case report describes an adolescent girl with polycystic ovarian syndrome and endogenously elevated androgen levels who developed a hepatic adenoma, suggesting a link between the two conditions.
11 citations
,
March 1991 in “PubMed” This study found that in female patients with androgenic hair loss and hirsutism, complex hormonal disturbances include elevated cortisol and thyroid hormone imbalances, rather than elevated androgen levels alone.
1 citations
,
January 2006 This article reviews the pathophysiology and causes of androgen-mediated hair growth in hirsutism but does not report any clinical outcomes; treatment aspects are discussed separately.
January 2014 in “European Geriatric Medicine” A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study found that hirsutism and acne are strong predictors of biochemical hyperandrogenism in women with polycystic ovary syndrome.
9 citations
,
September 2000 in “Obstetrics and gynecology clinics of North America” This article reviews the psychological impact of hirsutism, particularly its prevalence among women, and provides no new clinical findings.
April 2020 in “Journal of the Endocrine Society” This case report describes a 58-year-old woman whose virilization symptoms were linked to a steroid tumor of the ovary, emphasizing the importance of prompt diagnosis and treatment to improve her quality of life.
14 citations
,
January 2012 in “Endocrine development” This article reviews the challenges in diagnosing mild hyperandrogenism in adolescent girls, discussing potential causes like PCOS and treatment options, but reports no new clinical results.
1 citations
,
March 2012 in “Journal of pediatric & adolescent gynecology” This case report suggests that PCOS can present with virilization and rapidly increasing testosterone levels, and highlights oral contraceptives' effectiveness in managing hyperandrogenism in such cases.
October 2023 in “ANNALS OF PAKISTAN MEDICAL & ALLIED PROFESSIONALS” This study found that in women with PCOS, insulin resistance is closely associated with hyperandrogenism, indicating it may independently predict increased androgen levels.
3 citations
,
January 2012 in “Hanyang Medical Reviews” This review discusses the pathogenesis of hirsutism and related diagnostic criteria for polycystic ovary syndrome in Korean women, but reports no new clinical results.
23 citations
,
June 1997 in “Baillière's clinical obstetrics and gynaecology” This article discusses various diagnostic categories and treatments for hyperandrogenism, with a focus on polycystic ovary syndrome and reports no new clinical findings, calling for specific treatments and lifestyle changes.
26 citations
,
January 2020 in “Przegląd Menopauzalny” This review discusses the role of androgens in menopausal women's health, highlighting symptoms of both hyperandrogenemia and androgen deficiency, but reports no clinical results.
April 2020 in “Journal of the Endocrine Society” This case report describes a 22-year-old woman with hirsutism and irregular menstrual bleeding, diagnosed with an ovarian steroid cell tumor (NOS), whose androgen levels normalized after surgery.
1 citations
,
May 2013 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This study found that increased PSA levels in women with hyperandrogenism may serve as a diagnostic marker, comparable to free testosterone levels.
82 citations
,
May 2016 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This article outlines the clinical features, evaluation, and treatment strategies for androgen excess in polycystic ovary syndrome, highlighting important diagnostic and management approaches but reporting no new research results.
This article reviews the hormonal pathogenesis of acne vulgaris and androgenetic alopecia, emphasizing various hormonal factors beyond androgens, but reports no new clinical findings.