Hyperandrogenism in a Postmenopausal Woman Secondary to Testosterone-Secreting Ovarian Stromal Tumor with Acoustic Schwannoma

    December 2018 in “ Case reports in endocrinology
    Bindu Gandrapu, Preeyanka Sundar, Brian Phillips
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    TLDR A 63-year-old woman's male-like symptoms were caused by a rare testosterone-producing ovarian tumor, treated by removing her ovaries and fallopian tubes.
    In 2018, a case study was reported involving a 63-year-old postmenopausal woman who exhibited symptoms of hyperandrogenism, including severe alopecia, voice deepening, and clitoromegaly, due to a testosterone-secreting ovarian tumor. These types of tumors are uncommon and can be challenging to detect both clinically and radiologically. The woman's condition was initially undiagnosed until a biopsy revealed the presence of the androgen-secreting ovarian neoplasm. The recommended treatment for such cases, once other causes of high androgens are excluded, is bilateral salpingo-oophorectomy, which is the surgical removal of both ovaries and fallopian tubes.
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