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This review discusses the interplay of hyperandrogenism, insulin resistance, obesity, and their role in polycystic ovary syndrome, but presents no new clinical results.

In this study of premenopausal Iranian women with hirsutism, polycystic ovary syndrome was a common cause and frequently associated with menstrual irregularity, while elevated androgens or hyperandrogenic conditions were also observed.

This brief report discusses spironolactone used as a treatment for hirsutism in a hyperandrogenic woman, offering no new clinical findings and focusing on its antiandrogenic properties.

In this case report, the researchers described a postmenopausal woman with androgenic symptoms who was found to have a benign Leydig cell tumor of the left ovary, indicated by elevated testosterone levels and MRI findings, which was successfully treated with surgery.

This article reviews the causes, diagnosis, and treatment options for hirsutism in females, noting its connection to conditions like PCOS and highlighting the emotional distress it can cause.

In this case report, a 21-year-old woman with PCOS and obesity underwent bariatric surgery, leading to significant weight loss and improved hormonal balance, which alleviated her hyperandrogenism symptoms like hirsutism and irregular periods.

This case report describes a 36-year-old Pakistani phenotypic female diagnosed with 46,XY 5-alpha-reductase deficiency, highlighting that such disorders of sexual development can manifest with symptoms like obesity, hirsutism, and amenorrhea later in life due to unique circumstances.

This study synthesizes current evidence showing that menopause involves a predictable endocrine transition, while male ageing features a more variable testosterone decline, necessitating a nuanced clinical approach to diagnosis and treatment.

This review highlights the connection between sex hormones and metabolic dysfunction, emphasizing how conditions like male hypogonadism and female hyperandrogenism can increase the risk and severity of hepatic steatosis, which often progresses alongside metabolic syndrome and elevates mortality risks.

This study analyzed the relationship between clinical and anthropometric factors with the free androgen index to better evaluate polycystic ovarian syndrome, but results are not reported in the abstract.

This case report described a 9-year-old girl initially suspected to have complete androgen insensitivity syndrome, whose laboratory tests later suggested an alternative diagnosis involving atypical steroid metabolism patterns and hormonal responses.

This study found that inpatient dermatology consultations at a large tertiary care center often led to significant treatment changes, especially for complex skin conditions potentially linked to systemic diseases.

This review discusses hormone replacement therapy for menopausal women, emphasizing DHEA's unique ability to convert into sex steroids only in targeted tissues, and reports no new clinical results.

In this study, females with 5 alpha-reductase-2 deficiency exhibited decreased body hair, normal sebum production, and delayed menarche, suggesting a role for DHT in hair growth and menstrual function.

This study reported that 44% of hirsute women undergoing cyproterone acetate treatment experienced impaired sexual enjoyment, highlighting the need to inform patients about potential side effects.

This systematic review reported that gender-affirming hormone therapy may lead to changes in hair growth patterns, with differing effects for transgender men and women, potentially impacting quality of life.

This review discusses the molecular mechanisms of masculinization involving androgen signaling and their roles in male embryonic development and conditions like hypospadias and prostate cancer, and reports no clinical results.

This study found that plasma androgen levels tend to be lower than normal in patients with multiple pituitary hormone deficiencies, particularly those with ACTH deficiencies, and that human growth hormone treatment does not affect adrenal androgen secretion.

In this study, researchers observed that hyperandrogenic PCOS patients exhibited distinct miRNA and TGFβ signaling gene expression patterns in granulosa cells, suggesting these factors may play a role in PCOS pathogenesis.

This case study suggests a potential connection between insulin resistance-induced diabetes and the development of migraine symptoms in a patient with HAIR-AN syndrome, highlighting the importance of early diagnosis and a multifaceted treatment approach.

This review discusses the roles of androgens and androgen receptors in skin-related disorders and suggests that targeting androgen receptors may be a more effective treatment strategy.

This article discusses the role of dihydrotestosterone in human prostatic adenocarcinoma growth and suggests that 6-methyleneprogesterone could be used to inhibit DHT for treating hormone-responsive prostate cancer, without new clinical findings.

This study found that men with rapidly progressive male pattern baldness had elevated serum dehydroepiandrosterone sulfate levels, suggesting that adrenal hyperactivity may contribute to alopecia in genetically susceptible young men.

In this study, women with diffuse alopecia were found to have higher serum levels of adrenal androgen DHEAS, which may contribute to disrupted scalp hair growth.

This report presents a rare case of suspected 3β HSD deficiency in an adult female with symptoms like male pattern hair loss and low testosterone, suggesting a non-classical presentation.

Untreated Congenital Adrenal Hyperplasia can cause severe hair loss due to high androgen levels.

This study found that diagnosing non-classical 3 beta-hydroxysteroid dehydrogenase deficiency solely based on elevated serum or urinary 5-ene-steroids may not be reliable.

This study reports that in women with non-tumor hyperandrogenism, a decrease in serum testosterone from insulin-sensitizing therapy like metformin may indicate a low likelihood of having an androgen-secreting tumor.

This case study describes a 22-year-old woman with hirsutism who experienced symptom reversal through addressing nonclassical adrenal hyperplasia and polycystic ovaries alongside laser hair removal.

This study found that the normalized androgen ratio (NAR) could help evaluate androgen activity in women with acne vulgaris, hirsutism, and androgenetic alopecia, showing elevated NAR in some patients.