17 citations
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January 1995 in “The American Journal of Medicine” This review discusses the management of androgenic disorders in women, highlighting that treatment is generally more effective than recognized, though improvement may take weeks or months to appear.
January 2011 in “Yearbook of Dermatology and Dermatologic Surgery” Acne and hair loss are not good indicators of hormone imbalance in PCOS, but excessive body hair is.
192 citations
,
January 1976 in “The Journal of Clinical Endocrinology & Metabolism” This study observed that androgen levels rise with pubic hair development in Tanner stages, differing by sex and age, with DHEA showing a significant prepubertal increase especially in precocious adrenarche.
2 citations
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January 1989 in “PubMed” In this study, 48% of women with androgenetic alopecia showed hypothyroidism or hyperprolactinemia after TRH stimulation, suggesting these conditions may influence androgen metabolism and contribute to hair loss.
November 2022 in “Journal of the Endocrine Society” This case study reports that in an 8-year-old male, a pituitary adenoma causing isolated high LH secretion led to early testosterone-driven puberty without typical testicular enlargement, highlighting the differential roles of LH and FSH in pubertal development.
November 2021 in “Elsevier eBooks” This review discusses antiandrogen therapy for polycystic ovary syndrome, focusing on strategies to manage excessive androgen secretion, but it reports no new clinical results.
November 2023 in “JAAD case reports” This research indicates that androgens may drive hidradenitis suppurativa in some patients, as they show higher testosterone levels compared to nonaffected controls, and testosterone-lowering medications are established treatments for milder cases.
11 citations
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May 2009 in “Medical Hypotheses” This paper proposes a theory explaining how the normal anabolic effects of androgens lead to structural changes and hair follicle miniaturization, contributing to androgenic alopecia.
24 citations
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October 1994 in “Fertility and Sterility” This study suggests that in women with androgenic alopecia and men with premature balding, enhanced 5α-reductase activity and altered androgen conjugation, favoring sulfurylation, may be involved in scalp hair loss.
18 citations
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January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” In this study of hirsute women, researchers found that correlations between hirsutism and hyperandrogenism were observed only in patients with a low LH/FSH ratio.
January 2004 in “Anticancer Research” This study suggested that long-term finasteride treatment for BPH patients may induce neuroendocrine activity in the prostate, potentially increasing the risk of developing aggressive prostate cancer.
July 2023 in “Journal of Education, Health and Sport” This study found that while many women were aware of some symptoms and causes of androgen excess, there is a need to improve education on this endocrine disorder, especially among those without medical backgrounds.
8 citations
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March 2010 in “Gynecological Endocrinology” This study assessed various androgens' diagnostic effectiveness for hyperandrogenaemia in PCOS using ROC curve analysis, but it reports no specific new results.
4 citations
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January 2007 in “Gynecological endocrinology” This case study suggests that low leptin levels in obese hyperandrogenic postmenopausal women might indicate the presence of androgen-secreting tumors.
1 citations
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December 2022 in “Gynecological Endocrinology” This study found that among women with PCOS, higher HOMA-IR levels were associated with acanthosis nigricans, and increased DHEA-SO4, FAI, and FI values were linked to hirsutism.
September 2016 in “Gynecology Obstetrics and Reproductive Medicine” This review outlines the diagnostic criteria and management strategies for polycystic ovary syndrome, focusing on hyperandrogenism's cutaneous manifestations, such as hirsutism and acne, and describes treatments like oral contraceptives and antiandrogens to address these issues.
179 citations
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May 1982 in “The Journal of clinical investigation/The journal of clinical investigation” This study found that plasma 3 alpha-diol glucuronide was markedly elevated in women with idiopathic hirsutism, suggesting it may be a marker of peripheral androgen action.
17 citations
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September 2017 in “Journal of Cosmetic Dermatology” In this study of women with PCOS, hirsutism strongly correlated with metabolic abnormalities, while acne and androgenic alopecia were not clear markers of biochemical hyperandrogenemia or metabolic dysfunction.
1 citations
,
January 1971 Hormones, especially androgens, affect hair growth and can cause hair loss or excess hair in both men and women.
3 citations
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February 2021 in “JAMA Dermatology” Masculinizing hormone therapy increases the risk of hair loss in transgender and gender-diverse patients.
1 citations
,
July 2001 in “Pediatrics in review” This case report describes a 14-year-old girl with signs of virilization, including increased facial and body hair, deepened voice, and elevated serum testosterone and androstenedione levels.
April 2019 in “Journal of the Endocrine Society” In this case study, the researchers reported that treating a woman with type B insulin resistance using rituximab, dexamethasone, and cyclophosphamide greatly reduced her insulin needs, but her hyperandrogenic state persisted, suggesting ovarian hyperthecosis.
August 2025 in “Frontiers in Endocrinology” This study examined postmenopausal hyperandrogenism related to ovarian disease and found that specific biochemical markers can help differentiate between tumorous and non-tumorous cases, with a good level of sensitivity and specificity, supporting surgical intervention for resolution.
16 citations
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April 2007 in “Journal of Obstetrics and Gynaecology Research” In this study, serum PSA levels were higher in women with PCOS, suggesting it may serve as a marker for hyperandrogenism in this condition.
February 1999 in “Strength and Conditioning Journal” Androstenedione, a hormone supplement, doesn't improve muscle or performance and can cause harmful side effects.
32 citations
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November 1996 in “International Journal of Dermatology” This review discusses the use of antiandrogen therapy in dermatology, covering treatments for conditions like acne, hirsutism, and androgenic alopecia but reports no new clinical findings.
98 citations
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July 1983 in “Journal of Steroid Biochemistry” This study in the Arab population of Gaza described pseudohermaphroditism due to 17β-HSD deficiency, where individuals showed marked masculinization after puberty despite inadequate androgen proportions.
11 citations
,
August 2014 in “PubMed” This study found that women with acne had higher rates of hyperandrogenism and obesity, and higher androgen levels and BMI were linked to increased acne severity.
105 citations
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January 2009 in “Medicine” This study found that ethinylestradiol and high-dose cyproterone acetate significantly reduced hirsutism scores and were effective for treating acne and alopecia in women with hyperandrogenism.
12 citations
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December 2005 in “PubMed” This study suggests that some men with premature androgenic alopecia may have hormonal profiles similar to women with polycystic ovary syndrome, potentially indicating a male equivalent of the condition.