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Polycystic ovary syndrome is a complex condition that affects women's mental, reproductive, and metabolic health throughout their lives.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Obesity increases the risk of developing polycystic ovary syndrome, and weight loss can improve the condition.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Hidradenitis suppurativa treatment should be tailored to the individual, with quitting smoking being important.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

About 13% of women had idiopathic hirsutism and 8.5% had polycystic ovary syndrome in a group of Iranian women.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Flutamide effectively treats female pattern hair loss with low doses showing good liver tolerance.

The conclusion is that hirsutism should be diagnosed and treated because it affects quality of life and may signal other health problems.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

Hirsutism is excessive male-pattern hair growth in women, often caused by hormonal imbalances, and requires ongoing treatment to manage.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Cognitive behavioral strategies help women with PCOS make lifestyle changes to improve their health.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.