28 citations
,
April 2014 in “Hormones” This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.
26 citations
,
January 2020 in “Przegląd Menopauzalny” This review discusses the role of androgens in menopausal women's health, highlighting symptoms of both hyperandrogenemia and androgen deficiency, but reports no clinical results.
26 citations
,
January 2016 in “Indian journal of endocrinology and metabolism” In this randomized trial, metformin and pioglitazone both improved certain clinical and metabolic indices in women with PCOS, with pioglitazone showing potential as an alternate treatment for those intolerant to metformin.
25 citations
,
April 1988 in “Geburtshilfe und Frauenheilkunde” In this study, treatment targeting the estrogen-androgen balance reduced hair loss in 74 out of 104 women with androgenetic alopecia, with some experiencing hair regrowth.
24 citations
,
December 1988 in “British Journal of Dermatology” This study found no correlation between acne severity and clinical signs of androgenicity in women, suggesting factors other than hyperandrogenaemia may contribute to acne development.
21 citations
,
January 2017 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” This study suggests that acne is often associated with hyperandrogenemia in women, contradicting previous recommendations that acne is not linked to androgen excess disorders.
19 citations
,
March 2022 in “International Journal of Environmental Research and Public Health” This review covers the neuroendocrine aspects of polycystic ovary syndrome, focusing on hormones and neurotransmitters like GnRH and kisspeptin, but does not report new clinical findings.
19 citations
,
November 2012 in “Journal of Dermatological Treatment” In this study, isotretinoin treatment in women with severe acne increased body weight and triglycerides but did not affect androgens or insulin sensitivity.
17 citations
,
April 2010 in “Archives of Gynecology and Obstetrics” This study found that obese Taiwanese women had a lower incidence of acne than non-obese women, despite having higher serum testosterone levels.
17 citations
,
February 2004 in “PubMed” This review discusses symptom-driven treatment approaches for PCOS, focusing on ovulation induction, androgen reduction, and weight management, and reports recent advances like recombinant FSH and GnRH-agonist protocols without providing new clinical results.
16 citations
,
April 2012 in “Gynecological Endocrinology” This study found that older women with polycystic ovarian syndrome are more likely to experience metabolic syndrome and have different metabolic and reproductive profiles than younger women.
15 citations
,
January 2015 in “Clinical and Experimental Reproductive Medicine” This study reports that obesity significantly influences cardiovascular and metabolic disturbances in women with PCOS, with overweight women experiencing more severe symptoms compared to their non-obese counterparts.
14 citations
,
February 2016 in “Journal of Obstetrics and Gynaecology Research” In this study, the authors concluded that clinical hyperandrogenism is not a reliable predictor for biochemical hyperandrogenism in Thai women with PCOS.
14 citations
,
September 2015 in “Expert Opinion on Therapeutic Targets” This review discusses potential treatments for androgen excess in polycystic ovary syndrome and reports no new findings, emphasizing the importance of individualized antiandrogenic management to minimize side effects.
13 citations
,
August 2020 in “Der Hautarzt” This article discusses hyperandrogenism, including its symptoms, causes, and diagnostic approaches, and reports no new clinical results; it emphasizes the role of interdisciplinary care in treatment.
13 citations
,
September 2011 in “American Journal of Clinical Dermatology” This review describes the dermatological uses of the contraceptive ethinylestradiol/chlormadinone acetate for conditions linked to high androgen levels and reports no new clinical results.
11 citations
,
January 2012 in “International Journal of Endocrinology” In this study, the prevalence of insulin resistance in reproductive-aged Thai women with polycystic ovary syndrome was found to be 20%, with age, waist circumference, acanthosis nigricans, and dyslipidemia as significant predictors.
11 citations
,
November 2009 in “Sports Medicine” This review explores whether oligomenorrhoea in exercising women is a mild subclinical phenotype of PCOS or part of a spectrum of energy deficiency-related menstrual disturbances, without new clinical results.
10 citations
,
November 2018 in “Physiological Research” This review examines the methods and challenges in androgen laboratory diagnostics, discussing their advantages, limitations, and evolution; it presents no new experimental results.
10 citations
,
February 2007 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the early developmental origin of premature adrenarche and polycystic ovary syndrome and highlights potential utero-based mechanisms, reporting no new clinical findings.
9 citations
,
April 2015 in “Dermatologic Therapy” This review discusses the use of hormonal therapies for managing acne vulgaris in adult women and reports no new clinical results, emphasizing the chronic and severe nature of acne in this population.
9 citations
,
May 2008 in “Journal of Clinical Oncology” This article compiles references on toxic epidermal necrolysis and cutaneous reactions to anticancer agents but reports no new findings.
8 citations
,
June 2016 in “Journal of Cosmetic Dermatology” The study concluded that serum AMH is a useful tool for diagnosing polycystic ovarian morphology in women with persistent acne, potentially replacing transvaginal ultrasound, though it does not correlate with hyperandrogenemia.
8 citations
,
March 2010 in “Gynecological Endocrinology” This study assessed various androgens' diagnostic effectiveness for hyperandrogenaemia in PCOS using ROC curve analysis, but it reports no specific new results.
6 citations
,
June 2017 in “Reproductive Biomedicine Online” This study found that women with polycystic ovary syndrome in China had elevated androgen levels compared to healthy controls, and suggests body weight management and SHBG and FAI testing are recommended for these women.
5 citations
,
January 2019 in “cIRcle (University of British Columbia)” This research observed that women with PCOS may improve insulin resistance and reduce hyperandrogenism by increasing fiber and magnesium intake, and face higher anxiety symptoms potentially linked to societal appearance expectations.
5 citations
,
April 2013 in “Current Problems in Pediatric and Adolescent Health Care” This review discusses the prevalence and management of polycystic ovary syndrome in women, particularly noting gaps in understanding its presence in adolescents, and reports no new clinical findings.
5 citations
,
January 1985 in “Archives of Dermatology” This article reviews the complex relationship between androgenic hormones and skin disorders, emphasizing the need for further innovative research to understand varying skin responses, but it reports no new findings.
4 citations
,
January 2015 in “Türk Patoloji Dergisi” This review discusses the skin manifestations of endocrine diseases and reports no new clinical findings, emphasizing the importance of recognizing these signs for early diagnosis.
4 citations
,
March 2013 in “Neuropsychiatric Disease and Treatment” This case report describes a rare instance of a patient with anorexia nervosa who was subsequently diagnosed with Cushing's syndrome, highlighting diagnostic challenges due to overlapping symptoms.