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    Glossary Hyperammonemia

    condition with elevated ammonia levels in the blood

    Hyperammonemia is a condition characterized by elevated levels of ammonia in the blood. Ammonia is a waste product that is typically processed by the liver and converted into urea, which is then excreted in urine. When the liver is unable to effectively process ammonia, due to liver disease or genetic disorders affecting the urea cycle, it can accumulate in the bloodstream and become toxic, potentially leading to neurological symptoms such as confusion, lethargy, and in severe cases, coma.

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    Research 30 of 49

    1. Hyperammonemic encephalopathy without hepatic dysfunction due to treatment with valproate: four cases and a mini review Psychiatry and Clinical Psychopharmacology · 2018 · 7 citations
    2. Hyperammonemia with Valproic Acid: Colonic Ischemia Associated with “Triptan” Use Visual Side Effects with Pegylated Interferon: Alopecia Areata with Infliximab: Adverse Effects Seen with Medications Used for Irritable Bowel Syndrome Hospital pharmacy · 2004 · 2 citations
    3. TREATMENT OF VALPROATE‐INDUCED HYPERAMMONEMIA Journal of the American Geriatrics Society · 2005 · 12 citations
    4. Two Hypomorphic Alleles of Mouse Ass1 as a New Animal Model of Citrullinemia Type I and Other Hyperammonemic Syndromes ˜The œAmerican journal of pathology · 2010 · 35 citations
    5. The prevalence and management of side effects of lithium and anticonvulsants as mood stabilizers in bipolar disorder from a clinical perspective International Clinical Psychopharmacology · 2013 · 65 citations
    6. Serum Biotinidase Activity in Children Treated With Valproic Acid and Carbamazepine Journal of child neurology · 2009 · 16 citations
    7. Diagnosis and treatment of methylmalonic acidemia in 14 cases 2004 · 2 citations
    8. Valproic Acid is an Effective Anti-Emetic Treatment in Alexander Disease (P10-9.010) Neurology · 2023
    9. Hypertensive urgency in a child with focal epilepsy: Is it sodium valproate induced? Indian Journal of Pharmacology · 2022
    10. オルニチン・トランスカルバミラーゼ(OTC)欠損(spf・ash)マウスへのOTC遺伝子導入 1991
    11. Dramatic Clinical Improvement With Biotin Mega‐Dose Therapy in a Neonate With Holocarboxylase Synthetase Deficiency Molecular Genetics & Genomic Medicine · 2024 · 2 citations
    12. Curly Hair: A Rare Side Effect of Sodium Valproate in a Child Pediatric Oncall · 2019
    13. Methylmalonic Acidemia: Can Treatment be Improved? Journal of Nutritional Therapeutics · 2015
    14. Valproate-Associated Transaminitis and Rhabdomyolysis Curēus · 2023 · 2 citations
    15. Flares of systemic lupus erythematosus during pregnancy and the puerperium: prevention, diagnosis and management Expert Review of Clinical Immunology · 2012 · 87 citations
    16. Systemic causes of hair loss Annals of Medicine · 2016 · 18 citations
    17. Finasteride improves motor, EEG, and cellular changes in rat brain in thioacetamide-induced hepatic encephalopathy American Journal of Physiology-gastrointestinal and Liver Physiology · 2014 · 17 citations
    18. Biotinidase deficiency characterized by skin and hair findings Clinics in Dermatology · 2020 · 10 citations
    19. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    20. Inherited Disorders of the Hair Elsevier eBooks · 2013 · 2 citations
    21. Side Effects of Sodium Valproate among Children with Epilepsy under 2 Years of Age Scholars journal of applied medical sciences · 2020
    22. 1123 COPPER LOADING (CuL) STUDIES IN BRINDLED (Br) MOUSE HEMIZYGOTES AND HETEROZYGOTES Pediatric research · 1981
    23. Disorders of hair Journal of the American Academy of Dermatology · 1988 · 6 citations
    24. Normalization of hair growth in sparse fur-abnormal skin and hair (SPF-ASH) mice by introduction of the rat ornithine transcarbamylase (OTC) gene Journal of Dermatological Science · 1994 · 6 citations
    25. Liver transplantation for propionic acidemia in children Liver transplantation · 2011 · 76 citations
    26. The Role of Zinc in Gastrointestinal and Liver Disease Clinics in Gastroenterology · 1983 · 82 citations
    27. Pili torti in association with citrullinemia Journal of the American Academy of Dermatology · 1985 · 28 citations
    28. Long‐Term Management with Adipose Tissue‐Derived Mesenchymal Stem Cells and Conventional Treatment in a Dog with Hepatocutaneous Syndrome Journal of veterinary internal medicine · 2017 · 21 citations
    29. Clinical, biochemical and mutational findings in biotinidase deficiency among Malaysian population Molecular genetics and metabolism reports · 2019 · 8 citations
    30. A Case of Valproate Toxicity Related to Isoniazid Journal of Clinical Psychopharmacology · 2012 · 5 citations