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Some children in Malaysia with symptoms have either profound or partial biotinidase deficiency, and early testing and treatment are important.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Children taking higher doses of valproic acid had lower biotinidase activity, which may lead to biotin deficiency, but biotin supplements could help.

The conclusion is that genetic testing is important for diagnosing and treating various genetic hair disorders.

Pili torti is a rare condition where hair is twisted and breaks easily, often linked to genetic disorders or other health issues.

Some antiseizure medications can cause cosmetic problems like hair loss, excessive hair growth, acne, and gum overgrowth.

Cirrhosis affects quality of life with various symptoms, requiring a holistic, multidisciplinary approach for management.

Many pediatric epilepsy patients experience preventable severe adverse drug reactions, especially with certain medications and risk factors.

Sodium valproate caused vomiting in 20% of children under 2 years old, with other side effects like hair loss and loss of appetite also noted.

Not getting enough minerals can lead to health problems and shorter lifespans.

Certain vitamins in wrong amounts, alcohol abuse, metals, and other toxins can cause serious brain and nerve damage.

Finasteride may effectively reduce Tourette's syndrome symptoms and improve life quality.

Valproic acid can cause muscle damage and liver issues, which improve after stopping the drug.

Valproic acid can rarely cause reversible nail discoloration.

Hair thinning and loss in a girl with a rare metabolic disorder was linked to her condition.

The document concludes that hair analysis is not good for assessing nutrition but can detect long-term heavy metal exposure.

Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.

Ban Tu Wan, a Chinese herbal supplement, can cause severe liver damage.

Low dose valproate in epileptic children mainly causes weight gain and other non-life-threatening side effects.

The dog died from myxedema coma linked to severe atherosclerosis and thyroid issues.