CaBP1 and 2 are necessary for maintaining calcium currents and hearing in inner ear cells.
January 2007 in “UNIFESP Institutional Repository (Universidade Federal de São Paulo)” This study found that patients with chronic migraine who excessively use symptomatic medications had a higher prevalence of anxiety and mood disorders, suggesting these psychiatric diagnoses may influence medication overuse.
3 citations
,
October 2021 in “Neuroscience Letters” This study demonstrated the first successful isolation of inner ear exosomes from perilymph using a novel immunomagnetic technique, providing a potential diagnostic method for sensorineural hearing loss.
65 citations
,
January 2017 in “Postępy Dermatologii i Alergologii” This review highlights the increasing clinical applications of high-frequency ultrasonography in dermatology, particularly for assessing the depth of skin tumors and monitoring inflammatory skin diseases, but reports no new clinical results.
12 citations
,
June 2010 in “Journal of dermatology” This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.
October 2022 in “Deleted Journal” This case study reports intracranial hypertension in a 60-year-old woman linked to prolonged intake of low-dose Vitamin A from propolis capsules, highlighting a potential risk even at lower dosages.
2 citations
,
September 2022 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This article discusses the sensitive skin condition of the scalp, its clinical manifestations, triggers, and individualized treatment options, but reports no new clinical results.
2 citations
,
April 2017 in “Molecular Medicine Reports” In this study, blocking autophagy with 3-methyladenine significantly improved the survival of inner ear hair cells in a gentamicin-induced ototoxic mouse model.
1 citations
,
September 2025 in “Physiologia” This study found that systemic ovalbumin–aluminum sensitization followed by cutaneous challenge in mice induced thermal hyperalgesia, increased spinal cord gliosis, and sprouting of nociceptive fibers, along with elevated mast cell and nerve profile densities in the skin compared to controls.
8 citations
,
June 2021 in “International Journal of Molecular Sciences” In this study, UCMSC exosomes showed protective effects against cisplatin-induced hearing loss in mice by improving hearing and promoting cochlear tissue repair.
5 citations
,
January 2007 in “Annals of Internal Medicine” Folic acid might help with age-related hearing loss.
1 citations
,
December 2021 in “Kathmandu University medical journal” This article reviews the characteristics, common locations, and causes of epidermoid cysts, noting that surgical excision is the standard treatment, but it reports no new clinical findings.
1 citations
,
July 2024 in “Australasian Journal of Ultrasound in Medicine” In this study, researchers reported that cutaneous ultrasound may be a valuable tool in diagnosing and assessing inflammatory activity in tinea capitis, potentially guiding treatment decisions, especially in severe cases not apparent through clinical symptoms alone.
19 citations
,
February 2016 in “Journal of Biological Chemistry” In this study, researchers observed that knocking out KCNQ3 in mice increased firing frequencies in response to stimuli, particularly at slow mechanical indentation velocities, indicating a role in mechanosensory neuron sensitivity.
3 citations
,
January 2017 in “Journal of clinical and diagnostic research” This case series reported incidents of iatrogenic Cushing's Syndrome linked to high doses of intralesional corticosteroid injections and mesotherapy regimens, highlighting the need for cautious prescription practices and further research on mesotherapy safety.
July 2026 in “World Journal of Advanced Research and Reviews” In this report, an 80-year-old male with elevated serum IgG4 presented with a lesion suggestive of IgG4-related ophthalmic disease, but lack of orbital imaging and biopsy precluded definitive diagnosis, highlighting the necessity of excluding similar conditions before long-term treatment.
2 citations
,
September 2022 in “Scholarly journal of otolaryngology” This article reviews symptoms of post viral fatigue syndrome and long COVID, detailing various persistent symptoms, but reports no new clinical results.
November 2020 in “Journal of the American Academy of Dermatology” Intense pulsed light with radiofrequency showed mixed results in improving quality of life for hidradenitis suppurativa patients, with no clinical improvements.
1 citations
,
January 2022 in “Dermatology Reports” This study reported that sensitive scalp symptoms, including trichodynia, are frequently found in hair loss patients, particularly among those with telogen effluvium and alopecia areata.
10 citations
,
November 2008 in “Veterinary Dermatology” In this study, the misshaped and hairy ear phenotype in mutant mice was linked to mis-expression of certain Hoxc genes due to a chromosomal inversion.
7 citations
,
January 1996 in “In Practice” This article highlights causes of otitis externa in small animals and proposes an investigative approach; it reports no new findings.
May 2021 in “Journal of the Endocrine Society” This case study highlights the overlooked condition of opioid-induced adrenal insufficiency, emphasizing the need for increased clinician awareness of its potential prevalence in chronic opioid users.
71 citations
,
January 2012 in “PloS one” This study observed that after hair cell loss in the mouse cochlea, supporting cells were replaced by migrating non-specialised cells, with genetic background affecting the rate of tissue re-organization.
October 2025 in “Journal of the Endocrine Society” This case series highlights the risk of iatrogenic Cushing syndrome and adrenal insufficiency among immigrant patients using over-the-counter medications from other countries, which often contain hidden glucocorticoids marketed as vitamins, prompting clinicians to perform thorough medication histories for accurate diagnosis and management.
26 citations
,
October 2023 in “Neuroscience Bulletin” In this review, the authors discuss how understanding and co-regulating multiple signaling pathways could lead to effective regeneration of functional hair cells, highlighting current achievements and future approaches such as small molecule drugs and gene therapy for treating sensorineural hearing loss.
152 citations
,
April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study presents evidence that keratitis–ichthyosis–deafness syndrome is caused by a mutation in the connexin 26 gene, expanding the gene's known involvement in various disorders.
3 citations
,
April 1991 in “PEDIATRICS” This reply argues that children with isolated extraordinary daytime frequency do not require extensive testing or aggressive pharmacologic treatments, noting potential negative effects of oxybutynin.
1 citations
,
February 2025 in “Journal of Endocrinological Investigation” This review discusses the prevalence and clinical impact of menstrual abnormalities, acne, and hirsutism in young women with Cushing's syndrome and reports no new clinical results.
6 citations
,
November 2017 in “Journal of the Peripheral Nervous System” This study found that mercury chloride administration in rats led to decreased intraepidermal nerve fibers and increased Langerhans cells, suggesting small nerve fiber damage after mercury poisoning.
January 2026 in “JCEM Case Reports” This case report presents a rare instance of recurrent ACTH-independent Cushing’s syndrome due to PBMAH, coinciding with the development of a pheochromocytoma, highlighting the need for thorough reevaluation in similar recurring cases.