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Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Dermatologists need to understand hair products to treat hair and scalp issues better.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Too much androgen can cause hair loss; finasteride may help.

Modern science supports the use of some Ayurvedic plants for health, as ancient practices suggested.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Some vitamins and minerals like vitamin D and iron can help with certain types of hair loss, but more research is needed for others.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Combining liraglutide and metformin helps obese women with PCOS who didn't lose weight on metformin alone to lose more weight.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Postinflammatory hyperpigmentation causes dark skin patches and needs personalized treatment.

Melatonin helps regulate hair growth and protects the hair follicle from stress.