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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Experts recommend using evidence-based methods to diagnose and treat hirsutism, focusing on symptoms and underlying causes.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Polymeric nanoparticles show promise for treating skin diseases.

Niosomes are a promising, stable, and cost-effective drug delivery system with potential for improved targeting and safety.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

The Multi-Organ-Chip improves the growth and quality of skin and hair in the lab, potentially replacing animal testing.

Sebocytes play a key role in controlling androgen levels in human skin.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Chemotherapy can cause skin problems like hair loss, mouth sores, and skin darkening, and recognizing these can affect treatment decisions.

Chitosan nanofiber scaffolds improve skin healing and are promising for wound treatment.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Blocking JAK-STAT signaling can lead to hair growth.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Minoxidil boosts hair growth by increasing cell production and survival.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Low fluence photoepilation temporarily removes hair by targeting the hair follicle's pigmented area without severe damage.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.