October 2021 in “Journal of Investigative Dermatology” The study concluded that the developed models are effective for studying hair growth mechanisms and testing new treatments.
43 citations,
August 2010 in “Expert Opinion on Investigational Drugs” Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.
38 citations,
July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
November 2020 in “Journal of Bioengineering and Technology Apllied for Health” COVID-19 affects multiple body systems and complicates treatment; accurate testing is crucial.
Researchers created a new mouse model, G4, that mimics human PCOS symptoms and links the condition to a specific gene.
276 citations,
December 2017 in “Journal of Dermatological Science” The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.
14 citations,
November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
June 2023 in “Frontiers in Cardiovascular Medicine” Using existing drugs for new purposes could be a cost-effective way to treat chest pain and non-clogged heart arteries, with some drugs for lung blood pressure showing promise but needing more testing.
A new peptide, murikal/SPR4, was found to significantly increase hair growth in mice, and its liposomal topical formulations enhanced hair growth more than commercial products. However, results on human scalp skin were unclear, needing more tests.
1 citations,
April 2009 in “Wiley Encyclopedia of Forensic Science” Microscopic hair analysis helps identify species and sometimes individuals in forensic science.
June 2020 in “Journal of Investigative Dermatology” Red clover extract-based scalp treatments significantly improved hair volume and reduced hair loss and damage.
20 citations,
November 2021 in “Frontiers in cell and developmental biology” Skin organoids from stem cells could better mimic real skin but face challenges.
17 citations,
July 2018 in “International Journal of Cosmetic Science” Keratin-based particles safely improve hair strength, smoothness, and heat protection.
63 citations,
August 1996 in “Forensic Science International” Cosmetic treatments like bleaching and perming can greatly reduce opiate levels in hair, possibly leading to false-negative drug tests.
February 2024 in “Current Medicinal Chemistry” Minoxidil nanocrystals improved hair growth in mice more effectively and safely than regular Minoxidil.
19 citations,
March 2019 in “International Journal of Dermatology” The tattoo machine method safely delivers an average of 1,175 µg/cm² of medication into the skin.
8 citations,
September 2004 in “Contact dermatitis” Avoiding dyed wigs and clothing improved severe allergic reactions in a woman treated with diphencyprone.
February 2024 in “Skin health and disease” Exosomes could improve skin and hair treatments but are limited by cost, production difficulty, and need for more research.
October 2013 in “Journal of Medicinal Plants Research” The herbal cleanser increased hair growth in rats without harming their skin.
79 citations,
December 2017 in “Cosmetics” Effective sunscreen formulations can reduce skin absorption and enhance protection.
37 citations,
November 2007 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Black hair is fragile due to hair care practices, not structural differences.
31 citations,
April 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Androgens cause oil-producing skin cells with androgen receptors to mature and produce more oil.
127 citations,
April 1999 in “Journal of Investigative Dermatology” Rodent models helped understand psoriasis but none perfectly replicated the disease.
5 citations,
November 2017 in “Elsevier eBooks” Scientists can now grow hair-like structures in a lab using special 3D culture systems, which could potentially help people with hair loss or severe burns.
40 citations,
June 2013 in “Biomaterials” Scientists created 3D hair-like structures that could help study hair growth and test treatments.
20 citations,
June 1995 in “Tetrahedron Letters” New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.
16 citations,
February 2019 in “Journal of Cellular and Molecular Medicine” Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
January 2023 in “Journal of Cosmetics, Dermatological Sciences and Applications” The hair growth serum Trichosera® was effective in increasing hair regrowth and density and reducing hair fall without significant side effects.
9 citations,
January 2006 in “Cutaneous and ocular toxicology” L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.
8 citations,
December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Mouse models help understand alopecia areata and find treatments.