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Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Smad1 and Smad5 are essential for hair follicle development and stem cell sleepiness.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.

The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.

Future research on ectodysplasin should explore its role in diseases, stem cells, and evolution, and continue developing treatments for genetic disorders like hypohidrotic ectodermal dysplasia.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Wnt-10b is important for starting hair growth and developing hair follicles.

Hair loss in cancer patients can be related to the cancer itself, treatment, or other conditions, and understanding it is important for diagnosis and patient care.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Some skin conditions are common during pregnancy and can be safely treated without affecting the pregnancy outcome.

High levels of male hormones in pregnant mice cause heart enlargement and poor heart function in their female babies.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

Sonicated platelet-rich plasma boosts hair growth by activating stem cells.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

Most skin changes during pregnancy are harmless and moles don't significantly change, but many women experience pigmentation changes due to hormones and sun exposure.

Low-level laser therapy improves hair growth and dermal papilla cell function.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Skin cell-derived vesicles can help heal skin injuries effectively.

Operative hysteroscopy is still the main treatment for Asherman syndrome, but more research is needed on post-surgery methods.

Mutations in Plcd1 and Plcd3 together cause severe hair loss in mice.