29 citations
,
June 2017 in “Journal of Inherited Metabolic Disease” This review discusses the potential of using high-throughput and high-content screening methods for drug repositioning in rare diseases and reports no new results.
PRP therapy is a promising hair loss treatment for people with alopecia.
February 2018 in “InTech eBooks” This review discusses the role of platelet-rich plasma therapy in various cosmetic procedures, finding potential benefits in improving tissue homeostasis if harvesting standards are maintained, but reports no new clinical results.
May 2020 in “Research Square (Research Square)” In this study, stress hormone CRF was found to inhibit hair growth, suggesting that the HPA axis is functional in human dermal papilla cells and contributes to hair loss under stress conditions.
3 citations
,
April 2023 in “Urology Herald” This review discusses the use of platelet-rich plasma in urology and emphasizes the need for further multicenter studies to explore its potential benefits.
39 citations
,
January 2019 in “Cells” This review discusses the molecular mechanisms of Hutchinson-Gilford progeria syndrome and evaluates current research trends, available mouse models, and prospects for developing therapies, but reports no new clinical findings.
14 citations
,
April 2019 in “The Ukrainian Biochemical Journal” This study developed a simple method to prepare highly concentrated, resting platelet-rich plasma suitable for cell therapy, effectively preventing clotting while maintaining platelet reactivity and minimizing hemorrhage risk.
29 citations
,
December 1998 in “European Respiratory Journal” This study found that exposure to hair bleach aerosols containing persulphates and hydrogen peroxide induced airway hyperresponsiveness to acetylcholine in rabbits.
July 2025 in “Journal of Investigative Dermatology” Hhip-Cre effectively targets dermal papilla cells for gene manipulation in hair biology.
8 citations
,
March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports that the near-naked hairless mutation in mice is not an allele of the Hairless gene but may involve a mutation in a linked gene or a regulatory mutation.
4 citations
,
October 2007 in “PubMed” This study found that the PQ-70 shampoo formulation demonstrated the highest Hair Humidity Resistance Factor, indicating superior anti-frizz performance compared to other tested shampoos.
November 2025 in “International Journal of Advanced Research” In this case report, PRP therapy led to almost complete clearance of hypopigmentation in a 28-year-old Caucasian female after laser hair removal, suggesting PRP could be a promising treatment option for various hypopigmentation conditions.
17 citations
,
October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
1 citations
,
November 2011 in “Annales De Dermatologie Et De Venereologie” This article reviews clinical signs and treatment options for hyperandrogenism in women, emphasizing cyproterone acetate as the most effective antiandrogen for severe hirsutism, but reports no new clinical results.
October 2020 in “Journal of Aesthetic Nursing” The abstract discusses the potential of platelet-rich plasma as a new, efficient, safe, and reproducible solution for hair loss and thinning, highlighting advancements in growth factors and stem cell technology. However, this summary does not report specific findings or results.
January 2026 in “International Journal of Surgery Case Reports” This case series reports that home use of intense pulsed light devices may effectively reduce hair burden and prevent recurrence of pilonidal disease in patients unable to regularly attend clinic sessions.
8 citations
,
April 1997 in “Experimental Dermatology” This study found that hHbl gene expression is localized in the cortical cells of the human hair shaft and is notably high in pilomatricoma cells transitioning to hair shaft keratinocytes.
32 citations
,
July 2017 in “Oncotarget” This study found that intermittent treatment with FTI lonafarnib and sulforaphane may be a promising therapeutic approach for children with Hutchinson-Gilford progeria syndrome, as it improved the cellular phenotype.
17 citations
,
March 2012 in “Journal of biological chemistry/The Journal of biological chemistry” In this study, researchers found that overexpression of the hairless protein in Hr mutant mice disrupts inner root sheath formation by downregulating Dlx3 and associated keratins in hair follicle development.
6 citations
,
April 2009 in “Obstetrician & gynaecologist/The obstetrician & gynaecologist” This article reviews the assessment, causes, and management approaches for hirsutism in women, emphasizing ethical considerations concerning unapproved drug use and contraceptive responsibility but reports no new clinical findings.
10 citations
,
January 2000 in “PubMed” This study found that GnRH agonist treatment improved hirsutism scores more than finasteride after six months in women with idiopathic hirsutism, with both treatments causing no menstrual abnormalities or side-effects.
72 citations
,
October 2009 in “The FASEB journal” This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.
September 2025 in “Radboud University Press eBooks” This study investigated AHR signaling's role in skin biology and reported that novel AHR ligands may help restore keratinocyte function and reduce inflammation in skin diseases, suggesting their potential as therapeutic agents.
2 citations
,
January 2012 in “Journal of The Chilean Chemical Society” This study developed and validated a precise RP-HPLC-PDA method for estimating finasteride in bulk and tablet forms, suitable for quality control use.
10 citations
,
January 2010 in “Veterinary pathology” This study found that a newly identified mutation in the hairless gene in mice led to decreased Hr mRNA levels and changes in gene expression related to hair follicle development.
December 2021 in “International Journal of Research in Dermatology” This review examines the use of platelet-rich plasma for treating alopecia and highlights current challenges in preparation standards and efficacy, without presenting new clinical findings.
1 citations
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July 2007 in “Journal of Investigative Dermatology” The mutation causes hairless mice due to mislocalized and dysfunctional HR protein.
January 2020 in “Springer eBooks” This review discusses platelet-rich plasma as a treatment for hair loss and reports no clinical results; the authors note its potential as a minimally invasive option alongside existing therapies.
4 citations
,
June 2017 in “Anais Brasileiros De Dermatologia” This study demonstrates that miniaturized hair follicles in female pattern hair loss overexpress nuclear aryl hydrocarbon receptors, suggesting a potential role for environmental pollutants in this condition.
January 2023 in “Archives of Disease in Childhood Education & Practice” This article describes the causes of hirsutism, introduces a novel assessment tool, and suggests strategies for investigation and management, but provides no new experimental results.