26 citations
,
March 2018 in “Experimental Dermatology” This article argues that prolactin may have a role in sebaceous gland function and suggests it could be a potential target for treating skin conditions, but reports no new clinical findings.
98 citations
,
December 2008 in “Journal of Investigative Dermatology” This review discusses the possible impacts of prolactin on skin conditions like psoriasis, alopecia, and stress-related dermatoses, emphasizing the need for further research to explore its therapeutic potential.
3 citations
,
June 2024 in “International Journal of Molecular Sciences” In this review, the potential role of the hormone prolactin in skin biology and its implications for treating skin diseases and hair disorders are explored, with a focus on its stress-related impacts and possible immunomodulatory function in the context of COVID-19.
37 citations
,
March 2010 in “British Journal of Dermatology” Oestrogen and thyrotropin-releasing hormone affect prolactin and its receptor in human skin and hair, suggesting new treatment options for related conditions.
May 2013 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that women with hair loss had significantly higher free testosterone levels compared to those without hair loss.
August 2023 in “Journal of Clinical Medicine” This study found that metformin's effect on reducing prolactin levels is less pronounced in women with PCOS compared to control subjects, likely due to higher endogenous testosterone levels, despite improvements in insulin sensitivity in both groups after six months of treatment.
41 citations
,
September 1991 in “Medical hypotheses” This article reviews the potential role of prolactin as a neuroendocrine modulator in skin biology and pathology, discussing its relevance for conditions such as psoriasis and hair growth, but reports no new clinical findings.
146 citations
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January 2004 in “Hormones” This review explores the complex endocrine functions of human skin and its role as a peripheral endocrine organ, but reports no new clinical results.
24 citations
,
May 2010 in “Hautarzt” This review explores various hormone influences on hair growth and loss beyond androgens, noting that clinical hormone therapies for aging may impact hair due to associated hormone level reductions, but reports no new empirical results.
January 2023 in “Journal of applied animal research” This study found that short-day photoperiod treatment in Shanbei white cashmere goats enhanced cashmere growth, increased secondary follicle density, and altered hormone levels and gene expression related to hair follicle development.
August 2022 in “Theriogenology” This study found that allopregnanolone has a bimodal effect on prolactin secretion in sheep, stimulating PRL mRNA expression but inhibiting hormone release under stress and pregnancy conditions.
July 2024 in “International Journal of Chemical and Biological Sciences” This study reported that women with polycystic ovary syndrome had higher glypican-4 levels compared to controls, indicating its significant role in hormonal regulation associated with the condition.
40 citations
,
March 1982 in “British Journal of Dermatology” This study found that women experiencing diffuse hair loss had significantly lower levels of plasma sex-hormone binding globulin compared to controls, while their testosterone levels remained normal.
20 citations
,
July 2009 in “Experimental and Clinical Endocrinology & Diabetes” This study found that increased hair growth from Cyclosporin A treatment is likely not due to hormonal changes.
18 citations
,
December 2013 in “Colorectal Disease” This study found that women with pilonidal sinus disease had significantly higher prolactin levels compared to women without the disease, suggesting a possible link to its development.
2 citations
,
March 2020 in “Baghdad Science Journal” This study found that among men with Benign Prostatic Hyperplasia, treatment with the 5α-reductase inhibitor finasteride for three months significantly reduced levels of dihydrotestosterone and estradiol, hormones involved in prostate enlargement, without altering follicle-stimulating hormone or luteinizing hormone levels.
1 citations
,
October 2022 in “Springer eBooks” This review discusses the roles of hormonal pathways in regulating male sexual function, particularly highlighting the impact of testosterone, and reports no new research findings.
April 2025 in “Middle East Fertility Society Journal” This study established reference values for nine fertility hormones important in diagnosing and monitoring PCOS in Pakistani and other subcontinent populations.
March 2025 in “American journal of biochemistry & biotechnology/American journal of biochemistry and biotechnology” This study observed that individuals with hair loss had significantly higher levels of serum galanin, troponin, prolactin, and FSH, and lower levels of TSH, zinc, magnesium, copper, iron, and calcium compared to healthy controls, suggesting a potential role of these biomarkers in hair loss.
October 2023 in “Journal of the Endocrine Society” This case report describes a unique instance where elevated prolactin levels from a pituitary adenoma were associated with hirsutism due to increased dihydrotestosterone, with treatment leading to normalization.
December 2022 in “Cureus” This review discusses the hormonal impact on hair growth and the relationship between endocrine disorders and hair changes, reporting no new clinical results.
March 2020 in “Endocrinology research and practice.” In this study, treating prolactinoma with cabergoline normalized prolactin levels and affected some androgen-related parameters, but did not significantly improve hirsutism in affected women.
September 2019 in “Mağallaẗ Tikrīt li-l-ʻulūm al-ṣirfaẗ” This study reported that women with polycystic ovary syndrome had significantly higher concentrations of oxytocin, testosterone, luteinizing hormone, prolactin, and follicle-stimulating hormone compared to healthy controls.
January 2017 in “Clinical & medical biochemistry” This study observed that Greek Caucasian women with PCOS had distinct serum hormone levels and a specific AKT2 gene SNP, which may play a role in the condition's characteristics.
9 citations
,
September 2010 in “Immunology Endocrine & Metabolic Agents - Medicinal Chemistry” This article reviews how sex hormones and their analogues are used to treat diseases like autoimmune disorders and cancer, and discusses potential applications in infectious and parasitic diseases, without reporting new clinical results.
March 2025 in “Frontiers in Veterinary Science” In this study, altering the photoperiod in goats increased hormone concentrations and improved hair follicle development and skin antioxidant capacity, suggesting that short photoperiods may create favorable conditions for cashmere growth.
3 citations
,
January 1988 in “PubMed” This study observed that functional hyperprolactinemia in several women was associated with skin symptoms such as seborrhea, acne, and hair-related issues, resembling androgen-induced conditions.
2 citations
,
November 2013 in “Elsevier eBooks” This chapter discusses the role of hormones in regulating reproductive biology and outlines how the endocrine system, particularly the brain and pituitary gland, controls these hormonal processes.
56 citations
,
August 2005 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the complex interaction between androgens and hair follicle biology, highlighting the need for a better understanding to improve hirsutism treatments, but reports no new results.
51 citations
,
January 2003 in “Hormone Research in Paediatrics” This review discusses hormonal influences on hair growth and suggests that understanding hormone-gene interactions may improve treatment of hirsutism and alopecia, but reports no new clinical findings.