Does Cyclosporin A Influence Sex Hormone Level?
July 2009
in “
Experimental and Clinical Endocrinology & Diabetes
”
New to Hydrocortisone? There is a guide in the encyclopedia. Read the guide → Studysummary This study found that increased hair growth from Cyclosporin A treatment is likely not due to hormonal changes.
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The study investigated whether Cyclosporin A, known for causing hypertrichosis (hirsutism), influenced sex hormone levels. It involved 16 patients (5 female, 11 male) who developed hair overgrowth during Cyclosporin A treatment, compared to a control group on Azathioprine. Hormone levels, including serum androgens, prolactin, 17-hydroxyprogesterone, 17β-estradiol, and cortisol, were measured. Results showed no significant differences in serum androgens or prolactin levels between the groups, with 17-OHP and cortisol levels affected by cortisone treatment. The study concluded that Cyclosporin A-induced hair growth was not due to hormonal changes.
