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The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Using combined treatments can help manage acne by targeting the bacteria and skin changes that cause it.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The conclusion is that a more comprehensive and precise approach is needed for diagnosing PCOS to address its broader health risks.

Castration is preferred for non-breeding male dogs with BPH, but other treatments are available with specific pros and cons.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Alpha-blockers and 5-alpha reductase inhibitors are main treatments for BPH, with new support for phosphodiesterase-5 inhibitors and beta-3 agonists.

The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.

Untreated androgenetic alopecia leads to progressive hair loss in men.

AGA is a common hair loss affecting both genders, treated with various therapies to promote regrowth and slow thinning.

Dutasteride is a safe and effective treatment for hair loss.

Finasteride improves hair growth in men with androgenetic alopecia.

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Hair loss in men is common, treatable, but not curable.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Improving insulin sensitivity and weight loss can help manage polycystic ovary syndrome (PCOS).

PCOS is often linked to insulin resistance and obesity, and weight loss can improve symptoms.