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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Agmatine may help reduce seizures linked to hormone changes in female rats.

The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.

Menopause worsens skin, hair, and nails, affecting self-esteem and quality of life.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Hormonal status significantly affects women's skin health throughout their lives.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

After menopause, women lose a lot of skin collagen, but estrogen replacement might improve skin health.

Testosterone therapy and surgeries like mastectomy improve transgender men's lives and mental health with low risks and high satisfaction.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.

The document concludes that more inclusive research involving the transgender community is needed, especially on the neovaginal microbiome of trans women.

Insulin resistance plays a key role in PCOS, and lifestyle changes, weight loss, and medications like metformin can help manage it.

Combination of minoxidil and finasteride is more effective in increasing hair diameter than minoxidil alone for female-pattern hair loss.

A new tool can analyze hair to detect changes due to hormones, genetics, and aging.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.

Hormone treatment for transgender patients may not need to be stopped before surgery, but more research is needed, especially on estrogen.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Finasteride reduces testosterone conversion, progesterone lessens this, and levamisole enhances finasteride's effect.

Thyroid hormone may be useful for treating various skin conditions and needs more research.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.