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Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.

Hirsutism, excessive male-pattern hair in women, can be caused by high androgens or skin sensitivity, diagnosed by testosterone levels, and treated with hair removal and hormone therapy.

Cimetidine is not a first-choice treatment for female hair loss, and there's no consistently successful treatment for this condition in men or normal hormone level women.

Proper medical treatments can control and even reverse female pattern hair loss, but it's important to check for related conditions like excessive male hormone production, especially in severe cases.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

The most common skin issues in females with Polycystic Ovary Syndrome (PCOS) are excessive hair growth, hair loss, oily skin, acne, dark skin patches, and skin tags, which may be linked to hormone and insulin levels.

Opioid use may lower PSA levels, suggesting a possible role in prostate cancer control; PSA testing is useful for detecting prostate cancer; serum triglycerides are not linked to prostate cancer risk; and higher urethral PSA levels may be associated with local hormone activity.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Frontal fibrosing alopecia is a hair loss condition in postmenopausal women, similar to lichen planopilaris, with ineffective treatments.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Testosterone levels influence male behaviors and physical traits, but this relationship is complex and influenced by both internal and external factors.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Obesity is linked to various skin problems and may increase the risk of skin cancer.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Both estrogens and androgens are important for health in both males and females.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Uterine transplants for transgender women are feasible but need more research.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.