88 citations
,
June 2016 in “Human Reproduction Update” This review discusses developments in oral contraceptives, highlighting improved individualization, reduced side effects, and enhanced suitability for various women's health needs, but it reports no new clinical results.
76 citations
,
December 2009 in “Clinics in Dermatology” This review discusses the indications, contraindications, and potential for using hormonal therapy as a first-line treatment for acne in females, but reports no new clinical results.
31 citations
,
June 2015 in “British Journal of Dermatology” Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.
30 citations
,
March 2001 in “Environmental Health Perspectives” This review explores the significant impacts of hormonal changes within normal physiological ranges and suggests examining low-dose effects from chemicals disrupting hormonal activity; it presents no new clinical results.
26 citations
,
December 2016 in “Psychiatric Clinics of North America” This review describes current medical and surgical treatments for transgender men, highlighting the effectiveness and general tolerability of hormone treatment, and suggesting that surgical benefits often surpass associated risks, although it reports no new clinical findings.
24 citations
,
January 2001 in “Dermatologic clinics” This article reviews the use of hormonal therapies in dermatology, specifically focusing on their pathophysiologic rationale, indications, commonly used drugs, and pretreatment evaluations, and it reports no new research findings.
21 citations
,
October 2009 in “Dermatology” This study found that male pattern hair loss may be associated with differences in serum levels of androstenedione, cortisol, 17 beta-estradiol, and luteinizing hormone, compared to controls.
11 citations
,
April 2018 in “Nutrition Research” This review found that chromium supplementation has limited effects on weight reduction, glucose control, lipid profile, and hormonal balance in women with PCOS, highlighting the need for further research.
9 citations
,
January 2017 in “Journal of Clinical and Diagnostic Research” This article reviews the skin changes during pregnancy, categorizing them by their relation to pregnancy and highlighting cosmetic concerns, but reports no new results.
6 citations
,
February 2013 in “Medical Oncology” In this study, researchers reported that the SHBG +5790 G>A polymorphism was associated with an increased risk of developing resistance to hormonal castration in advanced prostate cancer patients.
6 citations
,
March 2012 in “Journal of the European Academy of Dermatology and Venereology” This study found that 12 cycles of chlormadinone acetate in hormonal contraceptives significantly improved oily skin and hair quality, enhancing psychosocial well-being in healthy women.
5 citations
,
March 2019 in “Facial Plastic Surgery Clinics of North America” In this article, the authors reviewed essential terminology and recommendations for creating a welcoming healthcare environment for transgender patients and providing gender-affirming therapy, emphasizing the unique health needs and disparities faced by this population.
5 citations
,
May 2017 in “Current Opinion in Pediatrics” This review found that hormonal therapies, including FDA-approved combined oral contraceptive pills and spironolactone, are effective and well-tolerated treatments for acne vulgaris in adolescents with or without endocrine disorders, providing alternative options to antibiotics.
2 citations
,
March 2001 in “Environmental Health Perspectives” Small hormonal imbalances can cause significant health problems, so more sensitive testing for hormone-disrupting chemicals is needed.
July 2024 in “Biological and Clinical Sciences Research Journal” This review reports that transgender individuals undergoing hormonal therapy for gender transition face increased risks of cardiovascular disorders, brain tumors, changes in bone density, metabolic disorders, and other health issues, while highlighting the necessity of this therapy for gender transformation.
1 citations
,
November 1996 in “Journal of Cutaneous Medicine and Surgery” Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.
216 citations
,
November 1999 in “Fertility and Sterility” This study found that a basal 17-hydroxyprogesterone level is effective for screening nonclassic adrenal hyperplasia in women, with a 4 ng/mL cutoff providing high specificity and positive predictive value.
120 citations
,
June 2008 in “American Journal of Epidemiology” This study reported a 6.3% prevalence of PCOS among women in a Sri Lankan community, with most cases presenting as oligo/amenorrhea and polycystic ovaries.
118 citations
,
September 2004 in “Clinics in Dermatology” This review discusses the role of hormones in acne vulgaris and highlights the need for further research on their mechanisms of action; it reports no new clinical results.
63 citations
,
January 2012 in “The European Journal of Contraception & Reproductive Health Care” This study concluded that combined hormonal contraceptives containing desogestrel, drospirenone, or cyproterone acetate were associated with a higher risk of venous thromboembolism compared to those containing levonorgestrel.
59 citations
,
September 2008 in “Experimental dermatology” This study reports that C3H/HeJ mice and DEBR rats serve as effective models for screening potential treatments for human alopecia areata, despite certain challenges in predictability and cost.
January 2025 in “ARC Journal of Dermatology” This study discusses the importance of careful dermatological care for transgender youth receiving hormonal therapies, cautioning that acne treatments can interfere with hormone replacement therapy and emphasizing the need for a collaborative interdisciplinary approach to support both acne management and overall well-being.
January 2024 in “Wiadomości Lekarskie” This source describes the implementation of a province-wide lung cancer screening program in Ontario, emphasizing that organized, program-based low-dose CT screening for high-risk populations is seen as more effective in reducing cancer incidence and mortality, while being cost-effective compared to non-organized screenings.
December 2023 in “Biointerface Research in Applied Chemistry” This study used molecular docking to identify stiripentol as a potential new inhibitor of the SRD5A2 enzyme, which is targeted for treating androgen-related diseases; however, in vivo trials are needed to validate its efficacy.
January 2023 in “The Annals of african surgery” This review concludes that preoperative hormonal stimulation with testosterone or DHT may help increase penile length and glans circumference, easing hypospadias surgery and potentially reducing postoperative complications.
188 citations
,
May 2009 in “Plant physiology” This study identified 19 specific genes involved in root hair growth and morphogenesis in Arabidopsis, using a combination of computational and experimental methods.
38 citations
,
October 1996 in “Dermatologic Clinics” This review discusses inflammatory and medication-related skin conditions associated with kidney disease and emphasizes the importance of timely referral to nephrology, reporting no new clinical results.
19 citations
,
August 2014 in “Journal of Ethnopharmacology” The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.
7 citations
,
December 2014 in “Gynecological Endocrinology” This study found that LC-MS/MS is a more reliable method than immunoassays for measuring serum 17OHP and androgen levels in women with hyperandrogenism.
3 citations
,
April 2021 in “Journal of Medicinal Chemistry” This study suggests that finasteride may inhibit the enzyme PNMT, potentially contributing to its sexual and psychological side effects.