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Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Tofacitinib and ruxolitinib are effective and safe for treating various autoimmune skin and joint disorders.

The medication combination did not affect glucose tolerance but increased some cholesterol levels due to its estrogen component.

Oral baricitinib and ruxolitinib are effective and safe for treating alopecia areata.

Exemestane is effective and safe for treating certain breast cancers, with mild side effects, but needs more research on long-term effects.

Saw palmetto supplements may reduce prostate cancer cell growth without being toxic.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Pharmacists should interpret lab data and perform physical exams to improve patient care.

Women with PCOS have higher hair cortisol levels, which are linked to worse metabolic and inflammatory conditions.

Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.

The document does not determine if adults with aphallia are fertile.

Doctors in the Middle East need better treatments and more knowledge about new therapies for hair loss condition Alopecia Areata.

Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.

Prenatal stress changes how male and female rats enjoy rewards differently, linked to sex hormones.

Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.

Obesity may worsen hair loss in men and increase hirsutism in overweight or obese individuals, with weight loss recommended for treatment.

Testosterone therapy can improve sexual function in women but long-term safety is unclear.

PCOS is a complex condition in women that can lead to health issues, and lifestyle changes are the best management approach.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Women under 55 with hair loss (AGA) may have a higher risk of heart disease (CAD).

Dermatologists are important in helping transgender people with skin issues and physical changes during their transition.

Both metformin and pioglitazone improve PCOS symptoms, but pioglitazone is a good alternative for those who can't take metformin.

Volatile organic compounds can cause inflammation and increase the risk of autoimmune diseases.

Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.

The method can measure multiple steroids in human hair to study long-term steroid metabolism, especially in newborns and children.

Combining yoga and certain herbs can effectively manage PCOS symptoms and improve quality of life.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Diagnosing and treating PCOS in teenagers is difficult, and the focus is on lifestyle changes and medication to improve health and prevent future issues.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.