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Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.

Flutamide combined with an LHRH agonist effectively inhibits prostate growth, suggesting it could treat prostate cancer.

Certain genetic variations are linked to increased androgen levels in PCOS, but more research is needed to understand these connections fully.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.

The document concludes that there is a significant lack of reporting on the sex and age of cells in skin research, which could affect clinical trials and treatments.

Forsythiaside-A, a natural substance, can protect against hair loss and is more effective than current treatments, potentially making it a good option for hair loss treatment.

Taking spironolactone and linestrenol for androgen excess can lead to lower bone density in young women.

An 81-year-old man's white hair began to regain its original color while he was treated with lenalidomide, suggesting that graying hair might be reversible.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Normal levels of DHT can reduce belly fat and increase muscle, but too much can lead to hair loss, prostate issues, and possibly heart disease.

The N363S gene variant does not cause higher adrenal androgen levels in women with polycystic ovary syndrome.

Children's hairlines change shape as they grow, with women often developing a widow's peak and men's hairlines becoming more convex and possibly balding at the temples, influenced by genetics and hormones.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

The document suggests that there might be an autoimmune link between polycystic ovary syndrome and Graves' disease.

Hormone imbalances can cause skin diseases, and understanding these links is important for diagnosis and treatment.

Oral contraceptives may cause hair loss in women.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Obesity changes androgen levels in women with PCOS, leading to higher testosterone relative to androstenedione.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

Certain genetic variations in OCT1 may improve insulin sensitivity with metformin in women with PCOS.

Outside factors like grooming, chemicals, and the environment can damage hair and cause disorders.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.